抗GATA结合蛋白3抗体
产品类别
兔抗人大、小鼠GATA3抗体
抗GATA结合蛋白3抗体
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
抗GATA结合蛋白3抗体
产品介绍
GATA-3属于转录调节性因子,表达在脑组织、胸腺中及其他很多组织中,并调节该类T细胞的发育和功能.Mol wt: 45-50kDa
The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.
mol wt:48kDa
Other Aliases:
GATA 3; GATA binding factor 3; GATA binding protein 3; HDR; MGC2346; MGC5199; MGC5445; Trans
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xy-2105xy Neuronal thread protein AD7c-NTP神经丝蛋白蛋白多肽
xy-0974xyB Oxytetracycline/BSA土霉素偶联牛血清白蛋白
xy-0974xyA Oxytetracycline/OVA土霉素偶联鸡卵白蛋白
抗GATA结合蛋白3抗体
xy-0283xy OVA (ovalbumin)鸡卵白蛋白
xy-0905xy Acetylated-P53(Lys382)抗肿瘤P53抗原
xy-0891xy Pokemon扑克蒙蛋白
xy-4867xy p70 S6 kinase beta核糖体蛋白S6激酶1
xy-0362xy Protein A蛋白A
xy-0563xy P-GP(P-glycoprotein)P-糖蛋白抗原
xy-3361xy Phospho-RIP2 (Ser176)磷酸化受体结合丝氨酸苏氨酸激酶2
xy-4545xyB Ractopamine/BSA莱克多巴胺与牛血清白蛋白偶联物
xy-4545xyK Ractopamine/KLH莱克多巴胺与血蓝蛋白偶联物
xy-2372xy rHBsAg 重组乙肝病毒表面抗原
xy-0295xy-AF647 Rabbit IgG/Alexa Fluor 647Alexa Fluor 647标记兔IgG(细胞流式同型对照)
xy-2037xyK streptomycin/KLH链霉素偶联血蓝蛋白
xy-5029xy SAHHS腺苷L-同型半胱氨酸水解酶
xy-3857xy SSDD/Steroid sulfatase类固醇硫酸酯酶
xy-2037xyB streptomycin/BSA链霉素偶联牛血清白蛋白
xy-0065xy SP (Substance P)P物质(抗原)
xy-3970xy SDHA琥珀酸脱氢酶复合体亚基A
xy-1175xy SHBG性激素结合球蛋白多肽
xy-0437xy-xyy5 Streptavidin/Cy5荧光素Cy5标记链霉亲和素
xy-0437xy Streptavidin, SA链霉亲和素
xy-2410xy SHBG性激素结合球蛋白多肽
xy-0726xy Survivin细胞凋亡抑制因子4(抗原)
xy-2037xyA streptomycin/OVA链霉素偶联鸡卵白蛋白
xy-0291xy THY (thyroglobulin,TG)甲状腺球蛋白
xy-0973xyB Tetracycline/BSA四环素偶联牛血清白蛋白
xy-6190xy Thyroxine Binding Globulin甲状腺素结合球蛋白抗原
xy-0973xyA Tetracycline/OVA四环素偶联鸡卵白蛋白
xy-0357xy TRH (Thyrotropin releasing hormone )促甲状腺素释放激素
xy-0392xy Thymopentin胸腺五肽
xy-0706xyB T4-BSA甲状腺素T4偶联牛血清白蛋白
xy-0387xy rh-TNF-Alpha(rh-Tumor Necrosis Factor alpha)重组人肿瘤坏死因子
xy-1411xy TERT端粒酶逆转录酶