丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体产品说明

    HtrA2/Omi是一种寡聚丝氨酸蛋白酶,存在于大部分的正常组织器官中,当细胞受到凋亡刺激时,HtrA2/Omi可由线粒体膜间隙(mitochondrial intermembrane space)释放进入细胞质中,导致出现大量的细胞凋亡性死亡, Omi/HtrA2 为促凋亡因子.

    Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP. 
    mol wt:50kDa 
    Other Aliases: 
    High temperature requirement protein a2; HTRA 2 ; HtrA like serine protease; HtrA serine peptidase 2; Omi stress regulated endoprotease; PARK 13; PARK13; Protease serine 25; PRSS 25; PRSS25; Serine protease 25; Serine protease HTRA2 mitochondrial; Serine protease htra2 mitochondrial precursor; Serine protease omi

xy-10171R PTOV1前列腺肿瘤高表达蛋白1抗体

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体

xy-5596R phospho-P53(Thr55)磷酸化肿瘤抑制基因P53抗体

xy-4180R P2Y2嘌呤ATP受体抗体

xy-2210R phospho-p38 MAPK (Thr180 + Tyr182)磷酸化丝裂原活化蛋白激酶p38抗体

xy-2219R Pectinesterase inhibitor 18果胶酶抑制蛋白18抗体

xy-3614R PPAR alphaα型-过氧化酶活化增生受体抗体（PPAR α, PPAR-α）

xy-2561R PSGD/HOXB13同源盒蛋白HOXB13抗体

xy-5537R Phospho-PDPK1(Ser393)磷酸化3磷酸肌醇依赖性蛋白激酶1抗体

xy-3716R Phospho-p63 (Ser160+Ser162)磷酸化P63肿瘤抑制基因抗体

xy-2270R Phospho-PAK4(Ser99)磷酸化p21激活激酶4抗体

xy-3717R Phospho-p73(Tyr99)磷酸化P73肿瘤抑制基因抗体

xy-3718R Phospho-p95 NBS1 (Ser343)磷酸化DNA修复蛋白NBS1抗体

xy-1573R PUMAp53正向细胞凋亡调控因子抗体

xy-4151R PLDL1磷脂酶C1样蛋白抗体

xy-6742R Prostate and colon associated protein前列腺癌和结肠癌相关蛋白

xy-0361R Protein G重组蛋白G抗体

xy-2067R PIK3CA磷脂酰肌醇激酶催化亚单位A抗体

xy-1476R PDI蛋白质二硫键异构酶抗体

xy-1345R PODXL足细胞特异蛋白抗体

xy-2090R P53(wt-p53)肿瘤抑制基因抗体（野生型P53）

xy-2413R PAX7配对盒基因7抗体

xy-0655R PAK5激活激酶PAK7抗体

xy-0420R PIBF孕激素诱导阻断因子抗体

xy-0754R PCNA增殖细胞核抗原抗体

xy-0491R PCNA增殖细胞核抗原抗体

xy-0665R PIWIL1piwi样1蛋白抗体

xy-0196R PDGF-A血小板源性生长因子A抗体

xy-0508R PRL泌乳素抗体

xy-0185R PDGF-B血小板源性生长因子-B抗体

xy-0231R PDGFRA血小板源性生长因子受体A抗体(PDGFRα)

xy-0232R PDGF Receptor beta血小板源性生长因子受体B抗体(PDGFRβ)

xy-0682R PDK4丙酮酸脱氢酶激酶4抗体

xy-0731R PEDF色素上皮源性因子抗体

xy-1084R PEG10肝癌高表达基因抗体

xy-0689R PEPT1肠道肽转运蛋白1/小肽转运蛋白1抗体

xy-0584R SLC15A2肠道肽转运蛋白2抗体