软骨蛋白聚糖/可聚蛋白多糖抗体

软骨蛋白聚糖/可聚蛋白多糖抗体

产品类别

 兔抗人、大、小鼠、犬、兔Aggrecan抗体

软骨蛋白聚糖/可聚蛋白多糖抗体

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 软骨蛋白聚糖/可聚蛋白多糖抗体

产品介绍

Aggrecan是软骨细胞外基质的主要结构成分之一.它与胶原蛋白网络结合，维持软骨弹性、缓冲压力，承担负荷,并有自我润滑的性能.蛋白多糖的进行性丧失是骨性关节病发病主要原因之一。

 Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS. 
    mol wt:250kDa 
    Other Aliases: 
    ACAN; AGC 1; AGC1; AGCAN; Aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); Aggrecan 1; Aggrecan core protein; Aggrecan proteoglycan; Aggrecan structural proteoglycan of cartilage; Aggrecan1; ATEGQV; Cartilage specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122; Chondroitin sulfate proteoglycan core protein 1; CSPG 1; CSPG1; CSPGCP; JSCATE; Large aggregating proteoglycan; MSK 16; MSK16; SEDK.

xy-0225R KLH血蓝蛋白抗体

xy-9857R KCNG2心脏钾离子通道蛋白亚基2抗体

xy-8358R KLHDC8AKLHDC8A蛋白抗体

xy-4894R Keratan Sulfate硫酸角质素抗体

xy-1577R KLF13肠道内富含的Kruppel样因子13

xy-9382R ZFP103锌指蛋白103抗体

xy-0734R KGF纤维母细胞生长因子7抗体

软骨蛋白聚糖/可聚蛋白多糖抗体

xy-2772R KLF2肺Kruppel样因子抗体

xy-5869R KLK5激肽释放酶5抗体

xy-5866R KLK13激肽释放酶13抗体

xy-5867R KLK15激肽释放酶15抗体

xy-5868R KLK2激肽释放酶2抗体

xy-5865R KLK12激肽释放酶12抗体

xy-2501R KiSS1 receptorG蛋白偶联受体54抗体

xy-3527R KIF17驱动蛋白家族KIF17抗体

xy-3644R KLF9转录因子KLF9抗体

xy-2531R NES/KLK10上皮细胞特异性蛋白1抗体

xy-5403R phospho-KCNC1(Ser503)磷酸化离子通道蛋白Kv3.1抗体

xy-2812R KAT4细胞周期基因1蛋白抗体

xy-2385R KLF5驱动蛋白KIF5B抗体

xy-7752R KLHL13kelch样蛋白13抗体

xy-11569R KCNN3钙激活钾通道蛋白3抗体

xy-11570R KIBRA肾脏和脑蛋白抗体

xy-7751R KIF2B有丝分裂驱动蛋白样2B抗体

xy-7753R KLHL9kelch样蛋白9抗体

xy-7804R KIF15驱动蛋白家族成员15抗体

xy-7808R KNTC1着丝点关联蛋白1抗体

xy-7806R KLHDC5kelch样蛋白5抗体

xy-7805R KIFC1驱动蛋白家族成员C1抗体

xy-7807R KLHL22Kelch样蛋白22抗体

xy-6671R KCND1电压门控钾通道Kv4.1抗体

xy-6674R KCNK3酸敏感钾离子通道蛋白3抗体

xy-2925R KlothoKlotho多肽蛋白抗体

xy-6675R KCNN4钙激活钾通道蛋白4抗体

xy-8049R KLHL23Kelch样蛋白23抗体

xy-8044R KBTBD10BTB-kelch蛋白家族10抗体

xy-8045R KBTBD4BTB-kelch蛋白家族4抗体

xy-8050R KLHL24Kelch样蛋白24抗体