抗诱捕受体2抗体

抗诱捕受体2抗体产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

抗诱捕受体2抗体产品介绍

    DcR1因缺乏细胞内信号传导系统而不能传递凋亡信号,但能竞争性与TRAIL（肿瘤坏死因子相关凋亡诱导配体）结合,有干扰凋亡信号的传导作用。

    Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L, a member of the TNF family, induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was identified and designated DcR2. The DcR2 receptor is 386 amino acids in length and has an extracellular TRAIL binding domain, but lacks intracellular death domain and does not induce apoptosis. Although this receptor binds to the cytotoxic ligand TRAIL, it contains a truncated death domain and functions as an inhibitory receptor. When overexpressed, the DcR2 receptor can protect cells against TRAIL mediated cytotoxicity. Like DR4 and DR5, DcR2 transcript is widely expressed in a variety of normal human tissues but DcR2 is absent in most tumors. Ultraviolet radiation has been shown to upregulate DcR2 expression on human keratinocytes. Over expression of DcR2 attenuated TRAIL induced apoptosis. 

    Also known as: 
Decoy receptor 2; CD 264; CD264 ; DcR 2; decoy with truncated death domain; ID; TNF receptor related receptor for TRAIL; TNF related apoptosis inducing ligand receptor 4; TNFRSF 10D; TNFRSF10D; TRAIL R4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRIALR 4; TRUNDD; Tumor necrosis factor receptor superfamily member 10d decoy with truncated death domain; Tumor necrosis factor receptor superfamily member 10D precursor

抗诱捕受体2抗体

hz-6754R YY1AP1/HCCA2  肝癌相关蛋白2抗体（转录因子YY1结合蛋白1抗体）

hz-6755R ZNF146  锌指蛋白146抗体

hz-6756R ZNF23  锌指蛋白23抗体

hz-6757R ZNF364/BCA2/RNF115  乳腺癌相关基因2抗体（锌指蛋白364）

hz-6758R FAM89B/MMTV-R  乳腺肿瘤病毒受体同源蛋白抗体

hz-6759R IL-11RA  白介素11受体α/IL-11Rα抗体

hz-6760R KCNQ-1  钾离子通道蛋白家族KCNQ1抗体

hz-6761R IL-10  白细胞介素-10抗体

hz-6762R LIPG/Endothelial lipase  内皮脂肪酶抗体

hz-6763R MSR1/CD204  巨噬细胞清道夫受体1/2/3抗体

hz-6764R NPC1/Nihzann Pick C1  尼曼匹克C1前体蛋白抗体

hz-6765R Perilipin A+B  脂滴包被蛋白A+B抗体

hz-6766R FLIP delta + gamma  凋亡调节蛋白δ+γ抗体

hz-6767R PDC6I/Alix  调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体

hz-6768R PEF1  调亡诱导因子家族蛋白PEF1抗体

hz-6769R PHAPI2/APRIL  酸性核磷蛋白32家族B抗体

hz-6770R DRAK1/STK17A  丝氨酸/苏氨酸蛋白激酶17A抗体（DAP凋亡诱导蛋白激酶1）

hz-6771R ERN2  内质网核信号转导蛋白2抗体

hz-6772R A1BG  α1B糖蛋白抗体

hz-6773R A1CF/Apo B RNA editing protein  载脂蛋白B-mRNA编码蛋白抗体

hz-6774R FASTKD1  Fas活化激酶结构域蛋白1抗体

hz-6775R FASTKD2  Fas活化激酶结构域蛋白2抗体

hz-6776R FASTKD5  Fas活化激酶结构域蛋白5抗体

hz-6777R HIPK3  Fas相互作用蛋白激酶3抗体

hz-6778R MAP3K9  丝裂原活化蛋白激酶3K9抗体

hz-6779R phospho-MAP3K9+MAP3K10(Thr312 + Thr266)  磷酸化丝裂原活化蛋白激酶3K9抗体

hz-6780R TYRO3/MER+SKY  受体酪氨酸激酶抗体

hz-6781R MLK2/MAP3K10  丝裂原活化蛋白激酶3K10抗体

hz-6782R MST4  丝氨酸/苏氨酸蛋白激酶MST4抗体

hz-6783R MAP3K14/NFkB Inducing Kinase NIK  丝裂原活化蛋白激酶3K14抗体

hz-6784R Cullin 5/CUL5  血管加压素激活钙启动受体蛋白1抗体

hz-6786R AQP8/Aquaporin 8  水通道蛋白8抗体

hz-6787R SLC26A4  钠碘单独转运蛋白SLC26A4抗体

hz-6788R Granzyme K  颗粒酶K抗体