肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗体

肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗体产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗体产品介绍

   肿瘤坏死因子相关的凋亡诱导配体(TNF related apoptosis inducingligand，TRAIL)又称凋亡素2配体(Apo2 ligand，Apo2L)或死亡配体，属于肿瘤坏死因子家族，能选择性的诱导肿瘤细胞凋亡，而正常细胞则可以逃逸他的杀伤作用，有望成为一种新的抗肿瘤方法。
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
    Alternative names:
    Apo 2 ligand; Apo 2L; APO2L; CD 253; CD253; CD253 antigen; Protein TRAIL; TL 2; TL2; TNF Related Apoptosis Inducing Ligand; TNF related apoptosis inducing ligand TRAIL; TNFSF 10; TNFSF10; TNFSF10 protein; TRAIL; TRAIL PEN; Tumor Necrosis Factor (ligand) Superfamily Member 10

肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗体

hz-1561R DTNBP1  精神分裂症易感基因抗体

hz-5852R ADAM20  去整合素样金属蛋白酶20抗体

hz-3607R DRP3/Dystrobrevin alpha  肌营养蛋白α抗体

hz-3548R DTNB  肌萎缩Dystrobrevin β蛋白抗体

hz-1721R dUTPase  脱氧尿嘧啶三磷酸核苷水解酶抗体

hz-1672R DPV(Duck plague virus)  鸭瘟病毒DPV抗体

hz-1748R DP-I  桥粒斑蛋白1抗体

hz-1749R DP-II  桥粒斑蛋白2抗体

hz-5853R ADAM23  去整合素样金属蛋白酶23抗体

hz-0598R DVL1  蓬乱蛋白1抗体

hz-5854R ADAM28  去整合素样金属蛋白酶28抗体

hz-0574R Dynamin 2  酶动力蛋白2抗体

hz-5855R ADAM32  去整合素样金属蛋白酶32抗体

hz-2304R Nadrin  神经细胞发育相关调控蛋白抗体

hz-2935R Nucleoporin p62  核孔糖蛋白P62抗体

hz-2429R Dysferlin  Dysferlin蛋白抗体

hz-0599R E2F1  转录因子E2F-1抗体

hz-5856R ADAMTS13  整合素样金属蛋白酶与凝血酶13型抗体

hz-4076R phospho-E2F1 (Ser364)  磷酸化转录因子E2F-1抗体

hz-5305R phospho-E2F1 (Ser337)  磷酸化转录因子E2F-1抗体

hz-5306R phospho-E2F1 (Ser332)  磷酸化转录因子E2F-1抗体

hz-1001R E2F2  转录因子E2F-2抗体

hz-5857R ADAMTS15  整合素样金属蛋白酶与凝血酶15型抗体

hz-1722R E2F3  转录因子E2F-3抗体

hz-1399R E2F4  转录因子E2F-4抗体

hz-1734R E2F5  转录因子E2F-5抗体

hz-1750R E2F6  转录因子E2F6抗体

hz-2305R E2EPF  泛素交联酶抗体

hz-4265R E2F8  转录因子E2F8抗体

hz-2071R E2 tag  E2 tag标签抗体

hz-0714R HPV16 E7 protein  人乳头瘤病毒16型E7抗体

hz-5860R ADAMTS9  整合素样金属蛋白酶与凝血酶9型抗体

hz-5861R ADAMTSL1  整合素样金属蛋白酶与凝血酶样1蛋白抗体

hz-1003R EAAT1/Glast  胶质细胞谷氨酸运载蛋白1抗体