眼睛和头发颜色相关蛋白FUZ抗体

英文名称    FUZ/FUZZY    

中文名称    眼睛和头发颜色相关蛋白FUZ抗体    

别    名    FLJ22688; fuz; FUZZY_HUMAN; Fy; Protein fuzzy homolog.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 眼睛和头发颜色相关蛋白FUZ抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    46kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FUZ/FUZZY    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

眼睛和头发颜色相关蛋白FUZ抗体产品介绍    background:

FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.

Function:
Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.

Subcellular Location:
Cytoplasm. Cytoplasm; cytoskeleton.

Similarity:
Belongs to the fuzzy family.

Database links:
UniProtKB/Swiss-Prot: Q9BT04.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

眼睛和头发颜色相关蛋白FUZ抗体

hz-1343P Ezrin/Radixin  埃兹蛋白（多肽）

hz-0949P F1 operon positive regulatory protein(NT)  鼠疫耶尔森氏菌F1荚膜蛋白(N端多肽）

hz-0950P F1 operon positive regulatory protein(CT)  鼠疫耶尔森氏菌F1荚膜蛋白(C端多肽）

hz-2135P FABP(brain) (Fatty acid-binding protein brain)  脑型脂肪酸结合蛋白抗原

hz-0511P FADD (Fas-associated protein with death domain)  Fas死亡结构域相关蛋白抗原

hz-1340P FAK(Focaladhesin kinase)  粘着斑激酶抗原

hz-1639P phospho-FAK(pTyr577)  磷酸化粘着斑激酶抗原

hz-1642P phospho-FAK(pSer732)(phospho-Focal adhesion kinase)  磷酸化粘着斑激酶抗原

hz-1765P FAST kinase(Fas-activated serine/threonine kinase)  Fas活化的丝/苏氨酸激酶抗原

hz-1157P FBN1 (fibrillin 1)  原纤维蛋白1抗原

hz-1256P FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4)  纤维母细胞生长因子4抗原

hz-1257P FGF5 peptide  纤维母细胞生长因子5抗原

hz-0809P Fibulin 1  衰老关键蛋白抗原

hz-1462P FLG(filaggrin)peptide  丝聚蛋白/中间丝蛋白抗原

hz-1170P FOS B  FosB抗原

hz-1188P FRA2/FOSL2(Fos related/like antigen 2)  FOS样抗原2

hz-2585P FOXF1(Forkhead box protein F1)  叉头蛋白F1抗原

hz-1775P FOXJ1/HFH-4 peptide  插头蛋白J1抗原

hz-1275P FoxP1(Forkhead box P1)  FoxP1（T细胞转录因子）抗原

hz-2687P FOXM1/HFH 11 peptide  插头蛋白M1抗原

hz-0886P Measles virus of fusion protein  麻疹病毒抗原（麻疹病毒融合蛋白）

hz-0895P FSH-R(Follicle-stimulating hormone receptor precursor)  促卵泡刺激素受体抗原

hz-1536P FSH(Follicle-stimulating hormone precursor)  促卵泡刺激素抗原

hz-1232P GABRA1(gamma-aminobutyric acid (GABA) A receptor, alpha 1)  γ1氨基丁酸A型受体α1抗原

hz-0533P GABAB1(GABAb Receptor 1)  g-氨基丁酸B1受体(多肽)

hz-1293P GABABR2/GB2(GABA B Receptor 2)  γ1氨基丁酸A型受体B2抗原

hz-1302P GAD-67 (glutamate decarboxylase 67)  谷氨酸脱羧酶-67抗原

hz-1361P GADD153(Growth arrest and DNA damage-inducible 153)  生长抑制DNA损伤基因153抗原

hz-1641P phospho GAP-43(pSer41)(phospho Growth associated protein 43 )  磷酸化神经生长相关蛋白43抗原

hz-0834P GAPDH  3-磷酸甘油醛脱氢酶(人)抗原

hz-2209P CXCR3/CD183 peptide  细胞表面趋化因子受体3抗原

hz-1452P GATA-3(GATA binding factor 3)  GATA结合蛋白3抗原