单跨膜蛋白FOXRED1抗体

英文名称    FOXRED1    

中文名称    单跨膜蛋白FOXRED1抗体    

别    名    FAD dependent oxidoreductase domain containing 1; FAD dependent oxidoreductase domain containing protein 1; FAD-dependent oxidoreductase domain-containing protein 1; FOXRED 1; FOXRED1; FP634; FXRD1_HUMAN; H17.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  神经生物学  信号转导  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 单跨膜蛋白FOXRED1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    54kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FOXRED1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

单跨膜蛋白FOXRED1抗体产品介绍    background:

FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential). 

DISEASE:
Defects in FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.

Database links:
UniProtKB/Swiss-Prot: Q96CU9.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.     

单跨膜蛋白FOXRED1抗体

hz-0358D-hzy5.5 Donkey Anti-Guinea pig IgG/Cy5.5  Cy5.5标记的驴抗豚鼠IgG

hz-0358D-hzy7 Donkey Anti-Guinea pig IgG/Cy7  Cy7标记的驴抗豚鼠IgG

hz-0358D-PE Donkey Anti-Guinea pig IgG/PE  PE标记的驴抗豚鼠IgG

hz-0358D-PE-hzy3 Donkey Anti-Guinea pig IgG/PE-Cy3  PE-Cy3标记的驴抗豚鼠IgG

hz-0358D-PE-hzY5 Donkey Anti-Guinea pig IgG/PE-CY5  PE-CY5标记的驴抗豚鼠IgG

hz-0358D-APhz Donkey Anti-Guinea pig IgG/APC  APC标记的驴抗豚鼠IgG

hz-0358D-AF350 Donkey Anti-Guinea pig IgG/Alexa Fluor 350  Alexa Fluor 350标记的驴抗豚鼠IgG

hz-0358D-AF488 Donkey Anti-Guinea pig IgG/Alexa Fluor 488  Alexa Fluor 488标记的驴抗豚鼠IgG

hz-0358D-AF555 Donkey Anti-Guinea pig IgG/Alexa Fluor 555  Alexa Fluor 555标记的驴抗豚鼠IgG

hz-0358D-AF647 Donkey Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的驴抗豚鼠IgG

hz-0358D-PE-hzy5.5 Donkey Anti-Guinea pig IgG/PE-Cy5.5  PE-Cy5.5标记的驴抗豚鼠IgG

hz-0358D-PE-hzy7 Donkey Anti-Guinea pig IgG/PE-Cy7  PE-Cy7标记的驴抗豚鼠IgG

hz-0358D-FIThz Donkey Anti-Guinea pig IgG/FITC  FITC标记的驴抗豚鼠IgG

hz-0358D-RBIThz Donkey Anti-Guinea pig IgG/RBITC  罗丹明标记的驴抗豚鼠IgG

hzm-0297M-RBIThz Mouse Anti-human IgG(3D3)/RBITC  罗丹明标记的鼠抗人IgG单克隆抗体

hzm-0297M-FIThz Mouse Anti-human IgG(3D3)/FITC  FITC标记的鼠抗人IgG单克隆抗体

hzm-0297M-Gold Mouse Anti-human IgG(3D3)/Gold  胶体金标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy3 Mouse Anti-human IgG(3D3)/Cy3  Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5 Mouse Anti-human IgG(3D3)/Cy5  Cy5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5.5 Mouse Anti-human IgG(3D3)/Cy5.5  Cy5.5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy7 Mouse Anti-human IgG(3D3)/Cy7  Cy7标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE Mouse Anti-human IgG(3D3)/PE  PE标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy3 Mouse Anti-human IgG(3D3)/PE-Cy3  PE-Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzY5 Mouse Anti-human IgG(3D3)/PE-CY5  PE-CY5标记的鼠抗人IgG单克隆抗体

hzm-0297M-APhz Mouse Anti-human IgG(3D3)/APC  APC标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF350 Mouse Anti-human IgG(3D3)/Alexa Fluor 350  Alexa Fluor 350标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF488 Mouse Anti-human IgG(3D3)/Alexa Fluor 488  Alexa Fluor 488标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF555 Mouse Anti-human IgG(3D3)/Alexa Fluor 555  Alexa Fluor 555标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF647 Mouse Anti-human IgG(3D3)/Alexa Fluor 647  Alexa Fluor 647标记的鼠抗人IgG单克隆抗体