旋转异构酶FKBP6抗体

英文名称    FKBP6    

中文名称    旋转异构酶FKBP6抗体    

别    名    36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; EC 5.2.1.8; FK506 binding protein 6; FK506-binding protein 6; FKBP 36; FKBP-36; FKBP-6; FKBP36; fkbp6; FKBP6_HUMAN; Immunophilin FKBP36; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP6; PPIase; PPIase FKBP6; Rotamase.    

说 明 书    0.1ml  0.2ml      

研究领域    心血管  发育生物学  生长因子和激素  t-淋巴细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 旋转异构酶FKBP6抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human IL-17F    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

旋转异构酶FKBP6抗体产品介绍    background:

FKBP6 is a 327 amino acid protein that, like other PPIases, accelerate the folding of proteins. As a component in synaptonemal complexes, FKBP6 is involved in homologous chromosomes pairing and male infertility in mice. There has been some suggestion that FKBP6 may play a role in modifying the susceptibility to idiopathic spermatogenic impairment in humans. Ubiquitously expressed in all tissues, FKBP6 is present at highest levels in testis, liver, kidney, skeletal muscle and heart. The gene encoding FKBP6 maps within a region of human chromosome 7 that has been implicated in Williams-Beuren syndrome, a rare developmental disorder involving abnormalities of the cardiovascular and musculoskeletal systems. Hemizygous deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome.

Function:
PPIases accelerate the folding of proteins.

Tissue Specificity:
Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.

DISEASE:
Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

Similarity:
Contains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats.

Database links:
UniProtKB/Swiss-Prot: O75344.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

旋转异构酶FKBP6抗体

hz-0374R-PE-hzy7 Rabbit Anti-horse IgM/PE-Cy7  PE-Cy7标记的兔抗马IgM

hz-0374R-AF647 Rabbit Anti-horse IgM/Alexa Fluor 647  Alexa Fluor 647标记的兔抗马IgM

hz-0326G-hzy3 Goat Anti-Bovine IgG/Cy3  Cy3标记的羊抗牛IgG

hz-0326G-hzy5 Goat Anti-Bovine IgG/Cy5  Cy5标记的羊抗牛IgG

hz-0326G-hzy7 Goat Anti-Bovine IgG/Cy7  Cy7标记的羊抗牛IgG

hz-0326G-PE Goat Anti-Bovine IgG/PE  PE标记的羊抗牛IgG

hz-0326G-PE-hzy3 Goat Anti-Bovine IgG/PE-Cy3  PE-Cy3标记的羊抗牛IgG

hz-0326G-PE-hzY5 Goat Anti-Bovine IgG/PE-CY5  PE-CY5标记的羊抗牛IgG

hz-0326G-APhz Goat Anti-Bovine IgG/APC  APC标记的羊抗牛IgG

hz-0326G-AF350 Goat Anti-Bovine IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗牛IgG

hz-0326G-AF488 Goat Anti-Bovine IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗牛IgG

hz-0326G-AF555 Goat Anti-Bovine IgG/Alexa Fluor 555  Alexa Fluor 555标记的羊抗牛IgG

hz-0326G-AF647 Goat Anti-Bovine IgG/Alexa Fluor 647  Alexa Fluor 647标记的羊抗牛IgG

hz-0326G-PE-hzy5.5 Goat Anti-Bovine IgG/PE-Cy5.5  PE-Cy5.5标记的羊抗牛IgG

hz-0326G-PE-hzy7 Goat Anti-Bovine IgG/PE-Cy7  PE-Cy7标记的羊抗牛IgG

hz-0326G-RBIThz Goat Anti-Bovine IgG/RBITC  罗丹明标记的羊抗牛IgG

hz-0326G-FIThz Goat Anti-Bovine IgG/FITC  FITC标记的羊抗牛IgG

hz-0326G-Gold Goat Anti-Bovine IgG/Gold  胶体金标记的羊抗牛IgG

hz-0326G-AP Goat Anti-Bovine IgG/AP  碱性磷酸酶（AP）标记的羊抗牛IgG

hz-0326G-hzy5.5 Goat Anti-Bovine IgG/Cy5.5  Cy5.5标记的羊抗牛IgG

hz-0326G-HRP Goat Anti-Bovine IgG/HRP  辣根过氧化物酶标记的羊抗牛IgG

hz-0326G-Bio Goat Anti-Bovine IgG/Bio  生物素标记的羊抗牛IgG

hz-0296G-Bio Goat Anti-Mouse IgG/Bio  生物素标记的羊抗小鼠IgG

hz-0296G-hzy3 Goat Anti-Mouse IgG/Cy3  Cy3标记的羊抗小鼠IgG

hz-0296G-hzy5 Goat Anti-Mouse IgG/Cy5  Cy5标记的羊抗小鼠IgG

hz-0296G-hzy5.5 Goat Anti-Mouse IgG/Cy5.5  Cy5.5标记的羊抗小鼠IgG

hz-0296G-hzy7 Goat Anti-Mouse IgG/Cy7  Cy7标记的羊抗小鼠IgG

hz-0296G-PE Goat Anti-Mouse IgG/PE  PE标记的羊抗小鼠IgG

hz-0296G-PE-hzy3 Goat Anti-Mouse IgG/PE-Cy3  PE-Cy3标记的羊抗小鼠IgG

hz-0296G-PE-hzY5 Goat Anti-Mouse IgG/PE-CY5  PE-CY5标记的羊抗小鼠IgG

hz-0296G-APhz Goat Anti-Mouse IgG/APC  APC标记的羊抗小鼠IgG

hz-0296G-AF350 Goat Anti-Mouse IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗小鼠IgG

hz-0296G-AF488 Goat Anti-Mouse IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗小鼠IgG