叉头蛋白B1抗体

英文名称    FOXB1    

中文名称    叉头蛋白B1抗体    

别    名    FKH 5; FKH5; Forkhead box B1; Forkhead box protein B1; FOX B1; FOXB 1; HFKH 5; Transcription factor FKH 5; Transcription factor FKH5; FOXB1_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    信号转导  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 叉头蛋白B1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    35kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FOXB1 (1-100aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

叉头蛋白B1抗体产品介绍    background:

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Function:
FOXB1 and FOXB2 are winged helix/forkhead transcription factors. FOXB1 is specifically expressed in the developing central nervous system (CNS). Early embryonic FOXB1 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. FOXB1 may play a role in postnatal growth, lactation and CNS development.

Subcellular Location:
Nuclear

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: Q99853.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

叉头蛋白B1抗体

hz-1414R HDAC1/HD1  组蛋白去乙酰化酶1抗体

hz-5387R phospho-HDAC1(Ser423)  磷酸化组蛋白去乙酰化酶1抗体

hz-5388R phospho-HDAC1(Ser423+Ser421)   磷酸化组蛋白去乙酰化酶1抗体

hz-1813R HDAC2/HD2  组蛋白去乙酰化酶2抗体

hz-5389R phospho-HDAC2(Ser394)  磷酸化组蛋白去乙酰化酶2抗体

hz-1819R HDAC3/HD3  组蛋白去乙酰化酶3抗体

hz-3174R Phospho-HDAC3 (Ser424)  磷酸化组蛋白去乙酰化酶3抗体

hz-2809R HDAC4  组蛋白去乙酰化酶4抗体

hz-2810R HDAC5  组蛋白去乙酰化酶5抗体

hz-2811R HDAC6  组蛋白去乙酰化酶6抗体

hz-3215R phospho-HDAC6 (Ser22)  磷酸化组蛋白去乙酰化酶6抗体

hz-2890R HDAC7  组蛋白去乙酰化酶7抗体

hz-3216R phospho-HDAC7 (Ser318)  磷酸化组蛋白去乙酰化酶7抗体

hz-2891R HDAC8  组蛋白去乙酰化酶8抗体

hz-3127R phospho-HDAC8(Ser39)  磷酸化组蛋白去乙酰化酶8抗体

hz-2892R HDAC9  组蛋白去乙酰化酶9抗体

hz-2893R HDAC10  组蛋白去乙酰化酶10抗体

hz-2894R HDAC11  组蛋白去乙酰化酶11抗体

hz-2895R HDAC12  组蛋白去乙酰化酶12抗体

hz-0287R His tag  聚组氨酸抗体标签抗体

hzm-0287M His tag(2D5)  小鼠抗聚组氨酸单克隆抗体

hz-3992R Hexokinase 1  己糖激酶1抗体

hz-3993R Hexokinase 2/HK2  己糖激酶2抗体

hz-3994R Hexokinase 3  己糖激酶3抗体

hz-0899R His tag(CT)  聚组氨酸抗体g标签抗体（C端）

hz-0833R FLAG Tag (NT)  FLAG Tag标签抗体（N端）

hz-0879R FLAG Tag (CT)  FLAG Tag标签抗体（C端）

hz-0965R FLAG Tag(CT)  FLAG Tag标签抗体（C端）

hz-2735R GstP1/GST class-pi  谷胱甘肽硫转移酶pi基因抗体

hz-2107R T7 tag  T7 tag标签抗体

hz-2109R V5 tag  V5 tag标签抗体

hz-2112R KT3 tag  KT3 tag抗体

hz-2110R VSV-G tag  VSV-G tag标签抗体