细胞分裂周期蛋白5抗体

英文名称    APC5    

中文名称    细胞分裂周期蛋白5抗体    

别    名    ANAPC 5; ANAPC5; Anaphase promoting complex subunit 5; Anaphase-promoting complex subunit 5; Apc 5; APC5; APC5_HUMAN; Cyclosome subunit 5; PDL 108; PDL108; Periodontal ligament fibroblast protein; RMC1.    

说 明 书    0.2ml      

研究领域    细胞生物  细胞周期蛋白  细胞分化      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞分裂周期蛋白5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    85kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human APC5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞分裂周期蛋白5抗体产品介绍    background:

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. 

Subunit:
The APC/C is composed of at least 12 subunits.

Similarity:
Belongs to the APC5 family. 
Contains 4 TPR repeats.

Database links:
UniProtKB/Swiss-Prot: Q9UJX4.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

细胞分裂周期蛋白5抗体

hz-0984P LH/CG Receptor(Luteinizing Hormone/Choriogonadotropin Receptor)  人促黄体生成素受体抗原

hz-1054P L-HDC (L-Histidine decarboxylase)  L-组氨酸脱羧酶抗原

hz-1058P LIF peptide  白血病抑制因子抗原

hz-1458P LIFR/CD118 peptide  白血病抑制因子受体抗原

hz-1177P Lingo-1  Nogo受体作用蛋白抗原

hz-2035P LIS1(Lissencephaly-1 protein)  无脑回的致病基因LIS1抗原

hz-0824P LFABP/FABP-1(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原

hz-0897P LFABP/FABP-2(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原

hz-0821P LN (laminin)  层粘连蛋白(多肽抗原)

hz-1526P Laminin Beta1 peptide  层粘连蛋白β1抗原

hz-1839P lamin A  核纤层蛋白A抗原

hz-2044P LOX-1/OLR1  凝集素样氧化型低密度脂蛋白受体

hz-0976P LPLUNC1  人鼻咽癌癌基因多肽抗原

hz-1311P LYVE-1(lymphalic vessel endotheilial hyaluronan receptor 1)  淋巴管内皮透明质酸受体抗原

hz-0439P ACE( ACE, testis-specific isoform precursor)  血管紧张素转换酶(抗原)

hz-2217P Integrin alpha E2 peptide  整合素alpha E2抗原

hz-1014P Mac-1 (Mac-1/CR3/CD11b+CD18)  巨噬细胞表面分子抗原

hz-0924P Mafa(avian)(V-maf musculoaponeurotic fibrosarcoma oncogene homolog A)  v-maf 肌腱膜纤维肉瘤癌基因同源物A抗原

hz-0817P MAGE-1  黑色素瘤相关

hz-1041P MAPKK1 (MAP kinase kinase 1)  丝裂原活化蛋白激酶激酶1抗原

hz-1425P ASK1/MAPKKK5  细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗原

hz-0792P Maspin (mammary serine protease inhibitor)  抑癌基因抗原

hz-0531P Matriptase  蛋白裂解酶（一种新的癌基因）抗原

hz-0808P HCMV UL49(Human Cytomegalovirus UL49 Gene)  人巨细胞病毒UL49抗原

hz-1419P MC-1R (melanocortin-1-receptor)  黑皮质素-1受体抗原

hz-1352P Mcl-1(myeloid cell leukhzia 1) peptide  髓样细胞白血病-1抗原

hz-1043P MDM2 (urine double minute 2)  双微体2癌基因抗原

hz-1468P MDR1(multidrug resistance 1)  多药耐药蛋白抗原

hz-1400P MEF2(myocyte enhancer-binding factor 2)  肌细胞增强因子2抗原

hz-0557P Mfn1 (Mitofusin1)  线粒体融合蛋白1

hz-1328P MT(metallothionein)  金属硫蛋白抗原

hz-0900P MGr1-Ag/37LRP(P37-kDa laminin receptor precursor)  层粘连蛋白受体1抗体

hz-0901P MGr1-Ag/37LRP(P37-kDa laminin receptor precursor)(CT)  层粘连蛋白受体1抗原（C端）