G蛋白偶联受体183抗体

英文名称    GPR183    

中文名称    G蛋白偶联受体183抗体    

别    名    ebi 2; EBI2; EBV induced G protein coupled receptor 2; EBV-induced G-protein coupled receptor 2; ebv-induced gene 2; Epstein-Barr virus-induced gene 2; Epstein Barr virus induced gene 2; epstein-barr virus induced gene 2; Epstein-Barr virus-induced G-protein coupled receptor 2; G protein-coupled receptor 183; G-protein coupled receptor 183; GP183_HUMAN; gpr183; Lymphocyte specific G protein coupled receptor.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细菌及病毒  G蛋白偶联受体  G蛋白信号  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 G蛋白偶联受体183抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    41kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EBV Induced Gene 2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.    

G蛋白偶联受体183抗体产品介绍    background:

Epstein-Barr virus-induced gene 2 is a 357 amino acid multi pass membrane protein. It is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. Ebi2 is a G-protein coupled receptor that signals through the G-protein G錳. Ebi2 contains seven hydrophobic transmembrane regions and a putative N-linked glycosylation site at its extracellular N-terminus. Ebi2 is believed to be involved in regulating the effects of the Epstein-Barr virus on B-lymphocytes. In addition, Ebi2 may play a role mediating normal lymphocyte functions.

Function:
Orphan receptor that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Gene ID:
1880    

G蛋白偶联受体183抗体

hze-0292P BSA/HRP   辣根过氧化物酶标记牛血清白蛋白

hze-0361P rec Protein G/HRP  辣根过氧化物酶标记的重组蛋白G

hz-0855P-HRP Insulin/HRP  辣根过氧化物酶标记人胰岛素蛋白

hz-0311P-AP Biotin/AP  碱性磷酸酶标记生物素

hz-0312P-AP Avidin/AP  碱性磷酸酶标记亲合素

hz-0437P-AP Streptavidin/AP  碱性磷酸酶标记链霉亲和素

hz-0360G-AP Goat Anti-human IgA/AP  碱性磷酸酶标记羊抗人IgA

hz-0360R-AP Rabbit Anti-human IgA/AP  碱性磷酸酶标记兔抗人IgA

hz-0362P-AP Protein A/AP  碱性磷酸酶标记的蛋白A

hz-0292P-AP BSA/AP  碱性磷酸酶标记标记牛血清白蛋白

hz-0361P-AP rec Protein G/AP  碱性磷酸酶标记的重组蛋白G

hzb-0360G Goat Anti-human IgA/Biotin  生物素化羊抗人IgA

hza-0297R Rabbit Anti-human IgG/Streptavidin  链霉亲和素标记兔抗人IgG

hzb-0295P Rabbit IgG/Biotin  生物素化兔IgG

hzb-0297P human IgG/Biotin  生物素化人IgG

hzb-0296P mouse IgG/Biotin  生物素化小鼠IgG

hzF-0292P BSA/FITC  荧光素标记牛血清白蛋白

hzF-0366R Rb Anti-FITC/FITC  荧光素标记兔抗FITC

hzF-0360G Goat Anti-human IgA/FITC  荧光素标记羊抗人IgA

hzR-0292P BSA/RBITC  罗丹明标记牛血清白蛋白

hzR-0437P Streptavidin/RBITC  红色荧光素罗丹明标记链霉亲和素

hzR-0295P Rabbit IgG/RBITC  罗丹明标记兔IgG(细胞流式同型对照)

hzR-0296P Mouse IgG/RBITC  罗丹明标记小鼠IgG(细胞流式同型对照)

hzR-0294P Goat IgG/RBITC  罗丹明标记羊IgG(细胞流式同型对照)

hzR-0293P Rat IgG/RBITC  罗丹明标记大鼠IgG(细胞流式同型对照)

hzF-0312P Avidin/FITC  荧光素标记亲合素

hzF-0437P Streptavidin/FITC   荧光素标记链霉亲和素

hzF-0361P rec Protein G/FITC  荧光素标记重组纯化蛋白G

hzF-0362P Protein A/FITC  FITC标记重组金黄色葡萄球菌蛋白A

hzR-0366R Rb Anti-FITC/RBITC  罗丹明标记兔抗FITC

hzR-0360G Goat Anti-human IgA/RBITC  罗丹明标记羊抗人IgA

hzR-0312P Avidin/RBITC  罗丹明标记亲合素

hzR-0362P Protein A/RBITC  罗丹明标记蛋白A