真核肽链释放因子1抗体

英文名称    eRF1    

中文名称    真核肽链释放因子1抗体    

别    名    Cl1 protein; D5S1995; ERF; eRF1; ERF1_HUMAN; ETF1; Eukaryotic peptide chain release factor subunit 1; Eukaryotic release factor 1; Eukaryotic translation termination factor 1; MGC111066; Polypeptide chain release factor 1; Protein Cl1; RF1; Sup45 (yeast omnipotent suppressor 45) homolog like 1; SUP45L1; TB3 1; TB3-1.    

说 明 书    0.2ml      

研究领域    细胞生物  转录调节因子  表观遗传学  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish, Arabidopsis Thaliana, Xenopus laevis    

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 真核肽链释放因子1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    49kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human eRF1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

真核肽链释放因子1抗体产品介绍    background:

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. [provided by RefSeq, Jan 2012]. 

Function:
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Subunit:
Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. 

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the eukaryotic release factor 1 family.    

真核肽链释放因子1抗体

hz-0015P IGF-II( Insulin-like Growth Factor-II )  胰岛素样生长因子-II（抗原）

hz-0392P TP-5(Thymopentin)  胸腺五肽

hz-0017P Galanin  神经节肽

hz-0841P GLP-2(Glucagon-like peptide-2)  胰高血糖素样肽-2蛋白

hz-0039P ADNP (NAP) (Activity-dependent Neuroprotective protein )  活性依赖的神经保护肽(抗原）

hz-0094P AACT(Alpha-1-Anti-chymotrypsin)  α-1抗胰糜蛋白酶

hz-2179P AACT protein(Alpha chymotrypsin protein)  胰糜蛋白酶

hz-0443P ACTH (Adrenorticotrophin hormons)(1-39)  促肾上腺皮质激素(1-39)（抗原）

Y-0133 ADM 1-52/AM 1-52 (Adrenomedullin 1-52)  肾上腺髓质素(1-52)

hz-0311PK Biotin/KLH  生物素偶联血蓝蛋白

hz-0311PB Biotin/BSA  生物素偶联牛血清白蛋白

hz-0442P ACTH (Adrenorticotrophin hormons)(18-39)  促肾上腺皮质激素（18-39）(抗原)

hz-0065P SP (Substance P)  P物质（抗原）

hz-0467P Ghrelin  脑肠肽(一种新的生长激素释放肽)多肽抗原

hz-0482P Gastrin(human)peptide(1-17)  胃泌素/蛙皮素（多肽人源）

hz-0337P myelin P0 prothein( peripheral myelin prothein Zero;MPZ;MPP)  外周髓鞘蛋白0(P0蛋白)多肽抗原

hz-0789P Insulin protein (from porcine pancreas)  猪胰岛素

P0005 bovine Insulin protein   牛胰岛素蛋白

hz-0865P Tachyplesin I(Tachyplesin-1 precursor )  抗菌肽

hz-0357P TRH (Thyrotropin releasing hormone )  促甲状腺素释放激素

hz-0435P PAR-2 AP (Protease-activated receptors-2 Activating polypeptide)  蛋白酶激活受体-2激活肽

hz-0590P Cygb (cytoglobin)  细胞球蛋白抗原

hz-0436P PAR-2 OP(Protease-activated receptors-2 Activating Orange-peptide)  蛋白酶激活受体-2桔抗肽

hz-0352P DLX4 (Dsital-less homebox4 isoformAlpha/ Beta)  末梢同源匡基因多肽片段

hz-0918P ShK(Stichodactyla helianthus Neurotoxin)  海葵神经毒素（35肽）

hz-1490P ShK(Stichodactyla helianthus Neurotoxin)-(Ala22)  海葵神经毒素（35肽）

hz-1491P ShK(Stichodactyla helianthus Neurotoxin)-(Arg22)  海葵神经毒素（35肽）

hz-1492P ShK(Stichodactyla helianthus Neurotoxin)-(Dap22)  海葵神经毒素（35肽）

hz-1320P ShK(Stichodactyla helianthus Neurotoxin)-(Gln9)  海葵神经毒素（35肽）

hz-1321P ShK(Stichodactyla helianthus Neurotoxin)-(Gln11)  海葵神经毒素（35肽）

hz-2000Pr rHBcAg  重组乙肝病毒核心抗原

hz-1662P rHBeAg(Hepatitis B Virus E Antigen protein)  重组乙肝病毒e抗原

hz-2005P rDen(rh-Dengue Virus)  多价重组人登革热病毒诊断抗原