血清反应因子辅助蛋白1抗体

英文名称    ELK4    

中文名称    血清反应因子辅助蛋白1抗体    

别    名    Elk4; ELK4_HUMAN; ETS domain containing protein Elk4; ETS domain protein; ETS domain-containing protein Elk-4; SAP-1; SAP1; Serum response factor accessory protein 1; SRF accessory protein 1; TCF1.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 血清反应因子辅助蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    47kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ELK4/SAP-1a    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

血清反应因子辅助蛋白1抗体产品介绍    background:

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

Function:
Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

Subunit:
Interacts with SIRT7.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.    

血清反应因子辅助蛋白1抗体

hz-0327R-PE-hzy5.5 Rabbit Anti-Bovine IgM/PE-Cy5.5  PE-Cy5.5标记的兔抗牛IgM

hz-0327R-PE-hzy7 Rabbit Anti-Bovine IgM/PE-Cy7  PE-Cy7标记的兔抗牛IgM

hz-0327R-AF488 Rabbit Anti-Bovine IgM/Alexa Fluor 488  Alexa Fluor 488标记的兔抗牛IgM

hz-0327R-AF555 Rabbit Anti-Bovine IgM/Alexa Fluor 555  Alexa Fluor 555标记的兔抗牛IgM

hz-0327R-HRP Rabbit Anti-Bovine IgM/HRP  辣根过氧化物酶标记的兔抗牛IgM

hz-0327R-Gold Rabbit Anti-Bovine IgM/Gold  胶体金标记的兔抗牛IgM

hz-0327R-Bio Rabbit Anti-Bovine IgM/Bio  生物素标记的兔抗牛IgM

hz-0327R-hzy3 Rabbit Anti-Bovine IgM/Cy3  Cy3标记的兔抗牛IgM

hz-0327R-hzy5 Rabbit Anti-Bovine IgM/Cy5  Cy5标记的兔抗牛IgM

hz-0327R-hzy5.5 Rabbit Anti-Bovine IgM/Cy5.5  Cy5.5标记的兔抗牛IgM

hz-0327R-hzy7 Rabbit Anti-Bovine IgM/Cy7  Cy7标记的兔抗牛IgM

hz-0327R-PE Rabbit Anti-Bovine IgM/PE  PE标记的兔抗牛IgM

hz-0327R-PE-hzy3 Rabbit Anti-Bovine IgM/PE-Cy3  PE-Cy3标记的兔抗牛IgM

hz-0327R-PE-hzY5 Rabbit Anti-Bovine IgM/PE-CY5  PE-CY5标记的兔抗牛IgM

hz-0327R-APhz Rabbit Anti-Bovine IgM/APC  APC标记的兔抗牛IgM

hz-0327R-AF350 Rabbit Anti-Bovine IgM/Alexa Fluor 350  Alexa Fluor 350标记的兔抗牛IgM

hz-0327R-AF647 Rabbit Anti-Bovine IgM/Alexa Fluor 647  Alexa Fluor 647标记的兔抗牛IgM

hz-0310R-Bio Rabbit Anti-chicken IgG/Bio  生物素标记的兔抗鸡IgG

hz-0310R-AF647 Rabbit Anti-chicken IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗鸡IgG

hz-0310R-AP Rabbit Anti-chicken IgG/AP  碱性磷酸酶（AP）标记的兔抗鸡IgG

hz-0310R-HRP Rabbit Anti-chicken IgG/HRP  辣根过氧化物酶标记的兔抗鸡IgG

hz-0310R-AF350 Rabbit Anti-chicken IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗鸡IgG

hz-0310R-AF488 Rabbit Anti-chicken IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗鸡IgG

hz-0310R-AF555 Rabbit Anti-chicken IgG/Alexa Fluor 555  Alexa Fluor 555标记的兔抗鸡IgG

hz-0310R-RBIThz Rabbit Anti-chicken IgG/RBITC  罗丹明标记的兔抗鸡IgG

hz-0310R-Gold Rabbit Anti-chicken IgG/Gold  胶体金标记的兔抗鸡IgG

hz-0310R-FIThz Rabbit Anti-chicken IgG/FITC  FITC标记的兔抗鸡IgG

hz-0310R-hzy3 Rabbit Anti-chicken IgG/Cy3  Cy3标记的兔抗鸡IgG

hz-0310R-hzy5 Rabbit Anti-chicken IgG/Cy5  Cy5标记的兔抗鸡IgG

hz-0310R-hzy5.5 Rabbit Anti-chicken IgG/Cy5.5  Cy5.5标记的兔抗鸡IgG

hz-0310R-hzy7 Rabbit Anti-chicken IgG/Cy7  Cy7标记的兔抗鸡IgG

hz-0310R-PE Rabbit Anti-chicken IgG/PE  PE标记的兔抗鸡IgG

hz-0310R-PE-hzy3 Rabbit Anti-chicken IgG/PE-Cy3  PE-Cy3标记的兔抗鸡IgG

hz-0310R-PE-hzY5 Rabbit Anti-chicken IgG/PE-CY5  PE-CY5标记的兔抗鸡IgG