羰基还原酶2抗体

英文名称    DCXR    

中文名称    羰基还原酶2抗体    

别    名    Carbonyl reductase 2; Carbonyl reductase II; DCR; Dcxr; DCXR_HUMAN; Dicarbonyl L xylulose reductase; Dicarbonyl/ L xylulose reductase; Dicarbonyl/L-xylulose reductase; HCR2; HCRII; Human carbonyl reductase 2; kiDCR; Kidney dicarbonyl reductase; L xylulose reductase; L-xylulose reductase; P34H; SDR20C1; Short chain dehydrogenase/reductase family 20C member 1; Sperm surface protein P34H; XR.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 羰基还原酶2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    26kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DCXR    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

羰基还原酶2抗体产品介绍    background:

DCXR is a 244 amino acid member of the short-chain dehydrogenases/reductases family. This peripheral membrane protein catalyzes NADPH-dependent reduction of mulitple sugars, including L-xylulose, to the osmolyte xylitol. Producing xylitol in the renal tubules can prevent osmotic stress. L-xylulose reductase functions as a homotetramer and is expressed highly in kidney, liver and epididymis. Essential pentosuria is the result of a partial deficiency of L-xylulose reductase. Red blood cells of normal individuals contain two L-xylulose reductases: a major and a minor isozyme. Red cells from patients with pentosuria contain only one isozyme. Due to its role in the uronate cycle of glucose metabolism, L-xylulose reductase has been implicated in the management of the long term complications of diabetes.

Function:
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Subcellular Location:
Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.

Tissue Specificity:
Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.

DISEASE:
Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.    

羰基还原酶2抗体

hz-2515 Human Pancreatic Polypeptide,PP ELISA Kit  人胰多肽

hz-2516 Human insulin autoantibodies,IAA ELISA Kit  人胰岛素自身抗体

hz-2517 Human glutamic acid decarboxylase,GAD ELISA Kit  人谷氨酸脱羧酶

hz-2518 Human Thymopentin,TP-5 ELISA Kit  人胸腺五肽

hz-2519 Human Thymosin ELISA Kit  人胸腺肽

hz-2520 Human Non-Phosphorylated Insulin-like growth factor binding protein 1 ELISA Kit  人未磷酸化类胰岛素生长因子结合蛋白-1

hz-2521 Human parathyroid hormone-like protein,PLP ELISA Kit  人甲状旁腺激素样蛋白

hz-2522 Human visfatin ELISA Kit   人内脂素/内脏脂肪素

hz-2523 Human apelin 12,AP12 ELISA Kit  人apelin 12

hz-2524 Human Glucose dependent insulin releasing polypeptide,GIP ELISA Kit  人葡萄糖依赖性胰岛素释放多肽

hz-2525 Human Proinsulin,PI ELISA Kit  人胰岛素原

hz-2526 Human Insulin Receptor Beta,ISR- Beta ELISA KIT  人胰岛素受体β

hz-2527 Human Glycated hhzoglobin A1c,GHbA1c ELISA Kit  人糖化血红蛋白A1c

hz-2528 Human ghcagons-like pepfide 1,GLP-1 ELISA Kit  人胰高血糖素样肽1

hz-2529 human thyroid stimulating immunoglobulin,TSI ELISA Kit  人甲状腺刺激免疫球蛋白

hz-2530 human Parathyroid hormone,PTH ELISA Kit  人甲状旁腺激素

hz-2531 human Prostaglandin D2-methoxime,PGD2-MOX ELISA KIT  人甲肟前列腺素D2

hz-2532 human Ultrasensitivity Thyroxine,u-T4 ELISA Kit  人高敏甲状腺素

hz-2533 human ultrasensitive thyroid-stimulating hormone,U-TSH ELISA Kit  人高灵敏度促甲状腺激素

hz-2534 human dopamine,DA ELISA KIT  人多巴胺

hz-2535 human Azidothymidine,AZT ELISA Kit  人叠氮胸苷

hz-2536 human adrencocorticotropic hormone,ACTH ELISA Kit  人促肾上腺皮质激素

hz-2537 human corticotropin releasing hormone,CRH ELISA Kit  人促肾上皮质激素释放激素

hz-2538 Human Thyroglobulin,TG ELISA Kit  人甲状腺球蛋白

hz-2539 Human Eukaryotic translation initiation factor 3a,eIF3a ELISA Kit  人真核翻译起始因子3a

hz-2540 Human phospho-extracellular signal-regulated kinase,pERK ELISA Kit  人磷酸化细胞外信号调节激酶

hz-2541 Human phospholamban,PLN ELISA Kit  人受磷蛋白

hz-2542 Human tumour necrosis factor related weak inducer of apoptosis,TWEAK ELISA Kit  人肿瘤坏死因子相关弱凋亡诱导因子

hz-2543 Human IPO-38 ELISA Kit  人IPO-38蛋白

hz-2544 human excision repair cross-complhzentation group 1,ERCC1 ELISA kit  人切除修复交叉互补基因1

hz-2545 Human Protein Carbonyl,PC ELISA Kit   人羰基化蛋白

hz-2546 human phospho-inhibitory subunit of NF-KapB Alpha,pIKB Alpha ELISA kit  人磷酸化核因子κB抑制蛋白α（IKKα human ELISA kit）

hz-2547 Human paxillin,Pax ELISA Kit  人桩蛋白