多能发育相关基因5抗体

英文名称    DPPA5    

中文名称    多能发育相关基因5抗体    

别    名    Developmental pluripotency associated 5; DPPA5; Embryonal stem cell specific gene 1 protein; Esg 1; ESG1; hDPPA5; DPPA5_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  发育生物学  干细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Rabbit,     

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 多能发育相关基因5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    13kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from Human DPPA5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

多能发育相关基因5抗体产品介绍    background:

DPPA5 is a 116 amino acid protein that localizes to the cytoplasm and contains one KH domain. Expressed in embryonic germ (EG), primordial germ (PG) and embryonic stem (ES) cells, DPPA5 plays an important role in the maintenance of ES cell pluripotency and may be necessary for proper embryogenesis. The gene encoding DPPA5 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
Dppa5 (sometimes known as Esg1) is expressed in mouse and human pluripotent cells and can be used as a marker of these cell types (Kim et al., 2005). 

Subcellular Location:
Cytoplasmic    

多能发育相关基因5抗体

hz-2030P NR1/NMDAR1/GLUR1(N-Methyl-d-Asprtate receptor 1)  谷氨酸受体1抗原

hz-2175P NR1/NMDAR1  谷氨酸受体1

hz-1067P NR2C/NMDAR2C(N-Methyl-d-Asprtate receptor 2C)  谷氨酸受体2C（多肽）

hz-1146P N-ras  原癌基因抗原

hz-1074P Nrf2 peptide  核因子2相关因子2抗原

hz-1342P NRF-1(nuclear respiratory factor-1)  核呼吸因子-1抗原

hz-1027P NSE (neuron specific enolase)  神经元特异性烯醇化酶抗原

hz-1958P NTCP(Na+/taurocholate Cotransporting Polypeptide)  钠离子/牛磺胆酸共转运蛋白抗原

hz-1375P Ghrelin 28  脑肠肽28

hz-1495P OCLN(Occluding)  咬合蛋白抗原

hz-1111P Oct-4(Octamer-4)  胚胎干细胞关键蛋白抗原

hz-1294P ODC(Ornithine decarboxylase)  鸟氨酸脱羧酶抗原

hz-2086P ompF(putative outer mhzbrane porin F protein)  小肠结肠炎耶尔森氏菌膜通道蛋白抗原

hz-2173P OLFM1 peptide  嗅球蛋白1多肽抗原

hz-1181P ORX-A(orexin-A)  增食欲素-A/欲激素A抗原

hz-1314P OTR(oxytocin receptor)  缩宫素受体

hz-1095P OXR (Orexin receptor)  食欲素受体(多肽)

hz-1483P P2P-R/RBBP6(proliferation potential protein related)  增殖潜能相关蛋白抗原

hz-0534P P19ARF  p19ARF抑癌基因抗原

hz-2210P phospho-p38 ERK/MAPK14 (pThr180/pTyr182) peptide  磷酸化丝裂原活化蛋白激酶p38抗原

hz-1689P MKK3(MAP Kinase Kinase 3)  丝裂原活化蛋白激酶MKK3/6抗原

hz-2090P P53(wt-p53)  肿瘤抑制基因抗原（野生型P53）

hz-0913P Mtp53(Mutant type p53)  突变型P53抗原

hz-0942P WIG-1(wtp53-induced gene 1)  野生型p53诱导基因1抗原

hz-1346P P73 protein  P73肿瘤抑制基因抗原

hz-1426P p70 S6 Kinase/P70 Beta1  p70S6Kb抗原

hz-0588P PALB2(partner and locaizer of BRCA2)  乳腺癌易感基因相关蛋白2

hz-1478P PAFR/PTAFR  血小板活化因子受体抗原

hz-2270P Phospho-PAK4 (Ser99) peptide  磷酸化p21激活激酶4多肽抗原

hz-0655P PAK7/PAK5/MBT  激活激酶PAK7/PAK5抗原

hz-0828P PAR-1 (Protease-activated receptors-1)  蛋白酶激活受体-1抗原

hz-1178P PAR-2 (Protease-activated receptors-2)  蛋白酶激活受体-2抗原

hz-1196P PAR4 (protease-activated receptor 4)  蛋白酶活化受体4/前列腺细胞凋亡反应蛋白4抗原