RAS相关抑细胞生长蛋白1抗体

英文名称    DIRAS1    

中文名称    RAS相关抑细胞生长蛋白1抗体    

别    名    Di Ras1; DIRAS family GTP binding RAS like 1; Distinct subgroup of the Ras family member 1; GBTS1; GTP binding protein Di Ras1; Ras related inhibitor of cell growth; RIG; Rig protein; Small GTP binding tumor suppressor 1.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  信号转导  转录调节因子  G蛋白偶联受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 RAS相关抑细胞生长蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    22kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DIRAS1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RAS相关抑细胞生长蛋白1抗体产品介绍    background:

The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.

Function:
Displays low GTPase activity and exist predominantly in the GTP-bound form.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).

Tissue Specificity:
Highly expressed in heart and brain.

Similarity:
Belongs to the small GTPase superfamily. Di-Ras family.

Database links:
UniProtKB/Swiss-Prot: O95057.1    

RAS相关抑细胞生长蛋白1抗体

hz-1474R CCL28/MEC  粘膜相关上皮趋化因子28抗体

hz-1710R CCR10  细胞表面趋化因子受体10抗体

hz-1780R CCRK  细胞周期相关激酶抗体

hz-0527R CD10/CALLA/Neprilysin  CD10抗体

hz-0579R CD105/Endoglin  CD105抗体

hz-4262R cIAP1/RNF48  凋亡抑制因子1抗体

hz-4609R CD105/Endoglin  CD105抗体

hz-5803R API2  凋亡抑制因子2抗体

hz-5536R TRAK1  驱动蛋白结合蛋白1抗体

hz-0672R CD117/c-kit/SCFR  干细胞生长因子受体/细胞表面分化抗原抗体

hz-1738R phospho-c-kit(Tyr936)  磷酸化原癌基因c-kit抗体

hz-3241R Phospho-c-Kit(Tyr703)  磷酸化原癌基因c-kit抗体

hz-3242R Phospho-c-Kit(Tyr721)  磷酸化原癌基因c-kit抗体

hz-5400R Phospho-c-Kit(Ser741)  磷酸化原癌基因c-kit抗体

hz-0395R CD133 antigen  造血干细胞抗原CD133抗体

hz-5814R Prominin 2  造血干细胞抗原CD133相关蛋白抗体

hz-0209R CD133 antigen  造血干细胞抗原CD133抗体

hz-2449R CD137/TNFRSF9  肿瘤坏死因子受体超家族成员9抗体

hz-1309R CD138/Syndecan 1  多配体蛋白聚糖1抗体

hz-1618R CD146/MCAM  黑色素瘤细胞粘附分子CD146抗体

hz-5472R phospho-MCAM(Tyr641)  磷酸化黑色素瘤细胞粘附分子CD146抗体

hz-1783R CD141/THBD  凝血调节蛋白/血栓调节素抗体

hz-4132R Ron  原癌基因c-Met相关酪氨酸激酶抗体

hz-5489R phospho-MST1R(Ser1349)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-5490R phospho-MST1R(Tyr1238)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-4138R MAPK11/p38Beta  丝裂原活化的蛋白激酶p38β抗体

hz-5506R phospho-MAPK11(Thr180+Tyr182)  磷酸化丝裂原活化的蛋白激酶p38β抗体

hz-4141R NUDEL/NDEL1  中心粒蛋白Nudel抗体

hz-4212R Neuroligin 1  突触细胞粘附分子1抗体

hz-5522R phospho-NDEL1(Ser231)  磷酸化中心粒蛋白Nudel抗体

hz-5523R phospho-NDEL1(Ser242)  磷酸化中心粒蛋白Nudel抗体

hz-5524R phospho-NDEL1(Thr219)  磷酸化中心粒蛋白Nudel抗体

hz-1383R CD13/APN/ANPEN  CD13氨肽酶N抗体

hz-1192R CD14  内毒素受体抗体