DNA损伤自噬调整蛋白抗体

英文名称    DRAM    

中文名称    DNA损伤自噬调整蛋白抗体    

别    名    Damage regulated autophagy modulator; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; dram1; DRAM1_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  心血管  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    IHC-P=1:100-500 IHC-F=1:100-500 DNA损伤自噬调整蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    26kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DRAM    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

DNA损伤自噬调整蛋白抗体产品介绍    background:

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

Function:
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Subcellular Location:
Lysosome membrane; Multi-pass membrane protein.

Similarity:
Belongs to the DRAM/TMEM150 family.

Gene ID:
55332

Database links:

Entrez Gene: 55332 Human

Entrez Gene: 71712 Mouse

Omim: 610776 Human

SwissProt: Q8N682 Human

SwissProt: Q9DC58 Mouse

Unigene: 525634 Human

Unigene: 35450 Mouse

DNA损伤自噬调整蛋白抗体 

hz-2562R COX7A2  细胞色素c氧化酶7A2抗体

hz-3934R COX3  细胞色素C氧化酶亚基3抗体

hz-2714R COX7A2  细胞色素c氧化酶COX7A2抗体

hz-3935R COX6B  细胞色素C氧化酶亚基6B抗体

hz-3763R Activin A Receptor Type IB  激活素受体1B抗体

hz-0804R ARIP2a  激活素受体2A抗体

hz-0857R Beta-arrestin 1  β-抑制蛋白1抗体

hz-3048R Phospho-beta-Arrestin 1(Ser412)  磷酸化β抑制蛋白1抗体

hz-1332R β-arrestin/ARRB2  β-抑制蛋白2抗体/β休止蛋白2抗体

hz-0801R ARIP2B  激活素受体2B抗体

hz-5027R ARP4  肝血管生成素相关蛋白抗体

hz-4006R ARSA  芳基硫酸酯酶A抗体

hz-0055R Arthzin  Arthzin抗体

hz-0600R ADRA1/ADRA1B/alpha 1 Adrenergic Receptor  alpha 1肾上腺素能受体抗体

hz-11001R FAM61B/LSM14B  FAM61B蛋白抗体

hz-11002R ESYT1/FAM62A  延伸突触蛋白1抗体

hz-11003R ESYT2/FAM62B  延伸突触蛋白2抗体

hz-11004R FAM63A  FAM63A蛋白抗体

hz-11005R RCS1/FAM64A  染色体分离调节蛋白1抗体

hz-11006R FAM70A  FAM70A蛋白抗体

hz-11007R FAM71A  FAM71A蛋白抗体

hz-11008R FAM71A  FAM71A蛋白抗体

hz-11009R FAM83F  FAM83F蛋白抗体

hz-11010R NSE1/FAM84A  感觉神经蛋白1抗体

hz-11011R FAM92A1  FAM92A1蛋白抗体

hz-11012R FAM98A  FAM98A蛋白抗体

hz-11013R ILDR1  免疫球蛋白样结构域受体1抗体

hz-11014R ILVBL  乙酰乳酸合成酶蛋白抗体

hz-11015R BFSP2/Phakinin  晶状体蛋白2抗体

hz-11016R GFAP delta  胶质纤维酸性蛋白GFAPδ抗体

hz-11017R NPTX2  神经细胞穿透素2抗体