诱捕受体3抗体

英文名称    DcR3    

中文名称    诱捕受体3抗体    

别    名    DcR3; Decoy Receptor 3; Decoy receptor for Fas ligand; DJ583P15.1.1; M68; OTTHUMP00000031583; TNF6B_HUMAN; TNFRSF6B; TR6; Tumor necrosis factor receptor superfamily member 6B; M68; Tumor necrosis factor receptor superfamily member 6b decoy; UNQ186/PRO212.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 诱捕受体3抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    30kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from mouse Decoy receptor 3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

诱捕受体3抗体产品介绍    background:

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.

Function:
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.    

诱捕受体3抗体

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hz-7632R MTFR1  线粒体裂变调节蛋白1抗体

hz-7633R MTP18  线粒体蛋白18抗体

hz-7634R PARL  骨骼肌细胞线粒体膜蛋白PARL抗体

hz-7635R GYPB/CD235b  血型糖蛋白δ抗体

hz-7636R FUT1  岩藻糖转移酶1抗体

hz-7637R ICAM4/CD242  细胞间粘附分子4抗体

hz-7638R RHCG  RH血型C糖蛋白抗体

hz-7639R SLC14A1/RACH1  尿素转运型糖蛋白抗体

hz-7640R XKR1  膜转运蛋白XK抗体

hz-7641R ACSM3  丁酰基辅酶A合成酶3抗体

hz-7642R AGTRAP  血管紧张素Ⅱ受体相关蛋白抗体

hz-7643R ARTS1  脂肪细胞源性亮氨酸氨基肽酶抗体（血管内皮细胞生长因子诱导蛋白）

hz-7644R NSPL2/RTN3  神经内分泌特异性蛋白2抗体

hz-7645R TID1/HCA57  肝癌相关抗原57抗体

hz-7646R FIS1/TTC11  线粒体裂变1蛋白抗体

hz-7647R VDAC3  线粒体外膜孔蛋白3抗体（电压依赖阴离子通道蛋白3）

hz-7648R DFFB  DNA断裂因子抗体（蛋白酶激活脱氧核糖核酸酶）

hz-7649R CIDE A  DNA断裂因子相似蛋白A抗体

hz-7650R CIDE B  DNA断裂因子相似蛋白B抗体

hz-7651R DNase I  脱氧核糖核酸酶1抗体

hz-7652R DNase II  脱氧核糖核酸酶2抗体

hz-7653R DNase gamma  脱氧核糖核酸酶γ抗体

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hz-7659R DATF1  死亡相关转录因子1抗体

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hz-7661R EAF2  睾酮调节细胞凋亡诱导和肿瘤抑制基因抗体