细胞色素P450 27B1抗体

英文名称    CYP27B1    

中文名称    细胞色素P450 27B1抗体    

别    名    1alpha(OH)ase; 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; 25-hydroxyvitamin D-1 alpha hydroxylase; 25-OHD-1 alpha-hydroxylase; Calcidiol 1-monooxygenase; CP27B_HUMAN; CP2B; CYP1; CYP1ALPHA; CYP27B; Cyp27b1; Cytochrome p450 27B1; Cytochrome p450 27B13; Cytochrome P450 family 27 subfamily B polypeptide 1; Cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1; Cytochrome P450 subfamily XXVIIB polypeptide 1; Cytochrome P450C1 alpha; Cytochrome P450VD1-alpha; mitochondrial; P450C1 alpha; P450c1; P450C1-alpha; P450VD1-alpha; PDDR; VD3 1A hydroxylase; VDD1; VDDR; VDDR I; VDDRI; VDR.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 细胞色素P450 27B1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    57kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CYP27B1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

产品介绍    background:细胞色素P450 27B1抗体

The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP27B1, a 508-amino acid protein that belongs to the XXVIIB subfamily of the cytochrome P450 family, localizes to the mitochondrion and is expressed in the kidney. The CYP27B1 protein catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) and functions in calcium metabolism, normal bone growth, and tissue differentiation. Mutations in the gene which encodes for CYP27B1 cause vitamin D-dependent rickets type 1 (VDDR-1), also designated pseudovitamin D deficiency rickets (PDDR), an autosomal recessive disease characterized by early onset of rickets with hypocalcemia and muscle weakness.

Function:
Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.    

细胞色素P450 27B1抗体

hze-0437P Streptavidin/HRP  辣根过氧化物酶标记链霉亲和素

hze-0362P Protein A/HRP  辣根过氧化物酶标记的蛋白A

hze-0292P BSA/HRP   辣根过氧化物酶标记牛血清白蛋白

hze-0361P rec Protein G/HRP  辣根过氧化物酶标记的重组蛋白G

hz-0855P-HRP Insulin/HRP  辣根过氧化物酶标记人胰岛素蛋白

hz-0311P-AP Biotin/AP  碱性磷酸酶标记生物素

hz-0312P-AP Avidin/AP  碱性磷酸酶标记亲合素

hz-0437P-AP Streptavidin/AP  碱性磷酸酶标记链霉亲和素

hz-0360G-AP Goat Anti-human IgA/AP  碱性磷酸酶标记羊抗人IgA

hz-0360R-AP Rabbit Anti-human IgA/AP  碱性磷酸酶标记兔抗人IgA

hz-0362P-AP Protein A/AP  碱性磷酸酶标记的蛋白A

hz-0292P-AP BSA/AP  碱性磷酸酶标记标记牛血清白蛋白

hz-0361P-AP rec Protein G/AP  碱性磷酸酶标记的重组蛋白G

hzb-0360G Goat Anti-human IgA/Biotin  生物素化羊抗人IgA

hza-0297R Rabbit Anti-human IgG/Streptavidin  链霉亲和素标记兔抗人IgG

hzb-0295P Rabbit IgG/Biotin  生物素化兔IgG

hzb-0297P human IgG/Biotin  生物素化人IgG

hzb-0296P mouse IgG/Biotin  生物素化小鼠IgG

hzF-0292P BSA/FITC  荧光素标记牛血清白蛋白

hzF-0366R Rb Anti-FITC/FITC  荧光素标记兔抗FITC

hzF-0360G Goat Anti-human IgA/FITC  荧光素标记羊抗人IgA

hzR-0292P BSA/RBITC  罗丹明标记牛血清白蛋白

hzR-0437P Streptavidin/RBITC  红色荧光素罗丹明标记链霉亲和素

hzR-0295P Rabbit IgG/RBITC  罗丹明标记兔IgG(细胞流式同型对照)

hzR-0296P Mouse IgG/RBITC  罗丹明标记小鼠IgG(细胞流式同型对照)

hzR-0294P Goat IgG/RBITC  罗丹明标记羊IgG(细胞流式同型对照)

hzR-0293P Rat IgG/RBITC  罗丹明标记大鼠IgG(细胞流式同型对照)

hzF-0312P Avidin/FITC  荧光素标记亲合素

hzF-0437P Streptavidin/FITC   荧光素标记链霉亲和素

hzF-0361P rec Protein G/FITC  荧光素标记重组纯化蛋白G

hzF-0362P Protein A/FITC  FITC标记重组金黄色葡萄球菌蛋白A

hzR-0366R Rb Anti-FITC/RBITC  罗丹明标记兔抗FITC

hzR-0360G Goat Anti-human IgA/RBITC  罗丹明标记羊抗人IgA

hzR-0312P Avidin/RBITC  罗丹明标记亲合素

hzR-0362P Protein A/RBITC  罗丹明标记蛋白A

hzR-0326P Bovine IgG/RBITC  罗丹明标记牛IgG

hzR-0327P Bovine IgM/RBITC  罗丹明标记牛IgM

hzR-0310P Chicken IgG/RBITC  罗丹明标记鸡IgG