羧基端小结构域磷酸酶1抗体

英文名称    CTDSP1    

中文名称    羧基端小结构域磷酸酶1抗体    

别    名    Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1; CTDS1_HUMAN; CTDSP1; NIF3; NLI IF; NLI interacting factor 3; NLI-IF; NLI-interacting factor 3; NLIIF; Nuclear LIM interactor interacting factor 3; Nuclear LIM interactor-interacting factor 3; SCP1; Small C-terminal domain phosphatase 1; Small CTD phosphatase 1.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  神经生物学  信号转导  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 羧基端小结构域磷酸酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    29kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CTDSP1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

羧基端小结构域磷酸酶1抗体产品介绍    background:

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Function:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.    

羧基端小结构域磷酸酶1抗体

hz-0118P AR (Androgen Receptor)peptide  雄激素受体（多肽抗原）

hz-1056P 5-HTR2A  5-羟色胺受体2A抗原

hz-1914P thrombin/Prothrombin  凝血酶Ⅱ(凝血因子II)抗原

hz-2126P 5-HTR3(5-hydroxytryptamine (serotonin) receptor 3a)  5-羟色胺受体3抗原

hz-2127P 5-HTR4(5 hydroxytryptamine serotonin receptor 4)  5-羟色胺受体4抗原

hz-1993P Muc2 peptide  粘蛋白-2/上皮膜抗原2抗原

hz-0733P ADAMTS7 peptide  整合素样金属蛋白酶与凝血酶1型-7抗原

hz-0045P AT (Angiotenogen)  血管紧张素原（抗原）

hz-0526P 5-LOX (5-lipoxygenase)  5-脂氧合酶抗原

hz-0733P-HRP ADAMTS7 peptide/HRP  辣根过氧化物酶标记整合素样金属蛋白酶与凝血酶1型-7抗原

hz-0167P Apo-E (Apolipoprotein E)  载脂蛋白E（抗原）

hz-2164P rhzOG 1-125 protein  重组髓鞘少树突胶质细胞糖蛋白1-125

hz-0245P IKI3 family protein  

hz-0317P ILK-1 (Integrin-linked protein kinase 1)  整合素连接激酶-1

hz-0114P Aromatase  芳香化酶（抗原）

hz-2337P SP-C peptide  肺表面活性蛋白C抗原

hz-2353P Mast Cell Chymase  肥大细胞类糜蛋白酶1

hz-2373P Ceruloplasmin peptide  铜蓝蛋白抗原

hz-2394P CKLF1  趋化素样蛋白

hz-0055P ART(Arthzin)(抗原)  

hz-1510P AATK peptide  细胞凋亡关联酪氨酸激酶抗原

hz-0261P AQP-2 (aquaporin Protein-2)  水通道蛋白-2（抗原）

hz-1627P ABCA1(ATP binding cassette transporter A1)  腺苷三磷酸结合盒转运体A1抗原

hz-2535P TFPI/LACI  组织因子途径抑制剂

hz-2540P GLUT12  葡萄糖转运蛋白12

hz-2558P EGFRvIII  表皮生长因子受体III型突变体抗原

hz-2570P CD26  CD26抗原

hz-1231P ABCG1 peptide  三磷酸腺苷结合盒亚家族G1抗原

hz-2804P Cardiac Troponin T  心肌特异性肌钙蛋白T

hz-0164P BACE( ASP2 )   β分泌酶（抗原）

hz-0583P ABL1(v-abl Abelson murine leukhzia viral oncogene homolog 1)  ABL1抗原

hz-2940P FUCA1/Alpha L fucosidase I peptide  α-L岩藻糖苷酶抗原

hz-0295P-AF647 Rabbit IgG/Alexa Fluor 647  Alexa Fluor 647标记兔IgG(细胞流式同型对照)

hz-0275P Bassoon(BSN)