英文名称 COPT2
中文名称 铜转运蛋白2抗体
别 名 AI604396; Copper transporter 2; COPT2; COPT2_HUMAN; CTR2; hCTR2; MGC117640; Probable low affinity copper uptake protein 2; RP23 64F17.2; SLC31A2; Solute carrier family 31 member 2; Solute carrier family 31, member 2.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 转运蛋白 新陈代谢
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 铜转运蛋白2抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COPT2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
铜转运蛋白2抗体产品介绍 background:
The activity of a diverse subset of enzymes relies on the essential nutrient copper to perform important processes including signaling to the transcription and protein trafficking machinery, oxidative phosphorylation, iron mobilization, neuropeptide maturation, and normal development. Copper uptake requires tight regulation to ensure that sufficient copper is present in the cell to drive vital cellular processes, while avoiding the accumulation of copper to toxic levels. The copper transporter 2 (COPT2), also designated CTR2 or Solute carrier family 31 member 2 (SLC31A2), is a 143 amino acid protein mediates the uptake of copper in mammalian cells. COPT2 has been shown to localize to the plasma membrane, endosomes and lysosomes, where it plays a role in maintaining copper homeostasis. COPT2 also mediates the uptake of the chemotherapeutic drugs cisplatin and carboplatin and may modulate the sensitivity and toxicity of these drugs.
Function:
Involved in low-affinity copper uptake.
铜转运蛋白2抗体
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hz-5369R phospho-GATA1(ser142) 磷酸化珠蛋白转录因子1抗体
hz-5370R phospho-GATA1(ser310) 磷酸化珠蛋白转录因子1抗体
hz-6616R GATA-2 GATA结合蛋白2抗体
hz-1452R GATA-3 GATA结合蛋白3抗体
hz-1778R GATA-4 GATA结合蛋白4抗体
hz-1779R GATA-5 GATA结合蛋白5抗体
hz-1787R GATA6 GATA结合蛋白6抗体
hz-5375R phospho-GATA6(Tyr271) 磷酸化GATA结合蛋白6抗体
hz-1250R Gax 生长终止特异性同源盒基因抗体
hz-5969R PLAG1 多型性腺瘤基因1蛋白抗体
hz-2768R GCN2 蛋白激酶GCN2蛋白抗体
hz-3155R Phospho-GCN2 (Thr899) 磷酸化蛋白激酶GCN2蛋白抗体
hz-3156R phospho-GCN2 (Thr667) 磷酸化蛋白激酶GCN2蛋白抗体
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hz-2551R CXCL9/MIG γ干扰素诱导单核细胞因子抗体
hz-2552R CXCL11 干扰素诱导T细胞趋化因子抗体
hz-2553R CXCL13/BCA1 B-淋巴细胞趋化因子抗体
hz-4509R CXCL13/BCA1 B-淋巴细胞趋化因子抗体
hz-2554R CXCL15/Lungkine 趋化因子CXCL15抗体
hz-1796R GCK/Glucokinase 葡萄糖激酶抗体
hz-0701R GCS/glucosylceramide synthase 谷氨酸半胱氨酸γ合成酶抗体
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hz-1023R CSF3/G-CSF 粒细胞-巨噬细胞集落刺激因子3抗体
hz-5116R GDIA1 肿瘤转移抑制基因GDIA1抗体
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hz-2356R GKRP 葡萄糖激酶调节蛋白抗体
hz-1794R GDF-1 生长、分化因子1抗体
hz-5099R GDF3 生长分化因子3抗体
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