L型电压依赖型钙通道β4抗体

英文名称    CACNB4    

中文名称    L型电压依赖型钙通道β4抗体    

别    名    CAB4; L-type Ca++ CPβ4; CACB4_HUMAN; Cacnb4; CACNLB4; Calcium channel voltage dependent beta 4 subunit; Calcium channel voltage dependent subunit beta 4; Calcium channel voltage-dependent subunit beta 4; Dihydropyridine sensitive L type calcium channel beta 4 subunit; EA5; EIG9; EJM; EJM4; Voltage-dependent L-type calcium channel subunit beta-4.    

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  信号转导  通道蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 L型电压依赖型钙通道β4抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    58kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CACNB4/L-type Ca++ CPβ4    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

L型电压依赖型钙通道β4抗体产品介绍    background:

Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.

Function:
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.    

L型电压依赖型钙通道β4抗体

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hz-1023R CSF3/G-CSF  粒细胞-巨噬细胞集落刺激因子3抗体

hz-5116R GDIA1  肿瘤转移抑制基因GDIA1抗体

hz-5126R GDIA2/ARHGDIB  肿瘤转移抑制基因GDIA2抗体

hz-2574R G-CSFR/CD114  粒细胞-巨噬细胞集落刺激因子3受体抗体

hz-2356R GKRP  葡萄糖激酶调节蛋白抗体

hz-1794R GDF-1  生长、分化因子1抗体

hz-5099R GDF3  生长分化因子3抗体

hz-1288R GDF8/MSTN  生长分化因子8抗体

hz-2227G GDF8  生长分化因子8/肌肉抑制素抗体

hz-1795R GDF9  生长分化因子9抗体

hz-3818R GDF15/MIC-1  生长分化因子15/巨嗜细胞抑制因子1抗体

hz-1024R GDNF  胶质细胞源性神经营养因子抗体

hz-5972R Ribonuclease 6  核糖核酸酶6抗体

hz-5973R SIRT7  沉默调节样蛋白SirT7抗体

hz-1160R Gelsolin  凝溶胶蛋白抗体

hz-4292R BPI  杀菌/通透性增强蛋白抗体

hz-0199R GFAP  胶质纤维酸性蛋白抗体

hz-5355R phospho-GFAP (Ser8)  磷酸化胶质纤维酸性蛋白抗体

hz-6193R SMYD2  组蛋白甲基转移酶SMYD2抗体

hz-5974R SMYD3  组蛋白甲基转移酶SMYD3抗体

hz-6108R SMYD4  组蛋白甲基转移酶SMYD4抗体

hz-5975R SSX8  滑膜肉瘤X断点蛋白8抗体

hz-0639R GFP  绿色荧光蛋白（免疫组化用抗体）

hz-0844R GFP  绿色荧光蛋白抗体

hz-0890R GFP  绿色荧光蛋白抗体

hz-2194R EGFP  重组增强型绿色荧光蛋白抗体

hz-5977R c-Maf  原癌基因cMAF抗体

hz-5976R c-Maf  原癌基因cMAF抗体

hz-5978R c-Myb  转录激活因子MYB抗体

hz-0168R GFRA4  GDNF家族受体α-4抗体

hz-0201R GFR Alpha-1  GDNF家族受体α-1抗体

hz-0654R GHR  生长激素受体抗体