19号染色体开放阅读框46抗体

英文名称    C19orf46    

中文名称    19号染色体开放阅读框46抗体    

别    名    Nesprin-4; Nesprin4; Nesprin 4; Chromosome 19 open reading frame 46; FLJ36445; Hypothetical protein LOC163183; SYNE4_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    心血管  细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 19号染色体开放阅读框46抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    44kDa    

细胞定位    细胞核 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human C19orf46    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

19号染色体开放阅读框46抗体产品介绍    background:

C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA.

Function:
Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).     

19号染色体开放阅读框46抗体

hz-9217R CST9/Cystatin 9  胱抑素9/半胱氨酸蛋白酶抑制剂9抗体

hz-9218R Cystatin S  胱抑素S/半胱氨酸蛋白酶抑制剂S抗体

hz-9219R C1orf149  1号染色体开放阅读框149抗体

hz-9220R C1orf187  1号染色体开放阅读框187抗体

hz-9221R C1orf177  1号染色体开放阅读框177抗体

hz-9222R C1orf183  1号染色体开放阅读框183抗体

hz-9223R RNF70  环指蛋白70抗体

hz-9224R RNF41  环指蛋白41抗体

hz-9225R RNF14  环指蛋白14抗体

hz-9226R RNF157  环指蛋白157抗体

hz-9227R RNF144  E3泛素蛋白连接酶144A抗体

hz-9228R RNF149  环指蛋白149抗体

hz-9229R RNF156  环指蛋白156抗体

hz-9230R RNF158  心脏蛋白磷酸酶1结合蛋白/环指蛋白158抗体

hz-9231R RNF166  环指蛋白166抗体

hz-9232R RNF167  环指蛋白167抗体

hz-9233R RNF180  环指蛋白180抗体

hz-9234R CREG1  E1A激活基因刺激蛋白1抗体

hz-9235R CDX1  尾侧型同源转录因子1抗体

hz-9236R CDX2/3  尾侧型同源转录因子2/3抗体

hz-9237R RNF35  环指蛋白35抗体

hz-9238R RNF23  环指蛋白23抗体

hz-9239R RNF24  环指蛋白24抗体

hz-9240R RNF25  环指蛋白25抗体

hz-9241R RNF31/HOIP  环指蛋白31抗体

hz-9242R RNF34  环指蛋白34抗体

hz-9243R RNF20  环指蛋白20抗体

hz-9244R RNF21  环指蛋白21抗体

hz-9245R RNF190  环指蛋白190抗体

hz-9246R RNF19B  环指蛋白19B抗体

hz-9247R RNF111  环指蛋白111抗体

hz-9248R RNF113A  环指蛋白113A抗体

hz-9249R RNF123  环指蛋白123抗体

hz-9250R TRAC1/RNF125  环指蛋白125抗体

hz-9251R RNF128  环指蛋白128抗体

hz-9252R RNF130/  环指蛋白130抗体

hz-9253R RNF133  环指蛋白133抗体

hz-9254R RNF138  环指蛋白138抗体