猪圆环病毒Ⅱ型衣壳蛋白

英文名称    capsid protein    

中文名称    猪圆环病毒Ⅱ型衣壳蛋白    

别    名    ORF1; ORF2 (PCV-2; PCV 2; Porcine circovirus2; Porcine circovirus-2.)    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  细菌及病毒      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    PCV2    

产品应用    ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）猪圆环病毒Ⅱ型衣壳蛋白 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    26kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from PCV2 capsid protein    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

猪圆环病毒Ⅱ型衣壳蛋白产品介绍    background:

There has been much uncertainty in the relationship between PCV2 and PMWS but Bolin et al demonstrated that Koch's postulates could be fulfilled by inoculating cesarean-derived, colostrum-deprived (CDCD) pigs with PCV2 and producing clinical signs of PMWS. Similar work has been performed using an infectious genomic clone of PCV2 in specific pathogen free (SPF) pigs to produce the gross and microscopic lymphoid lesions of PMWS. Although PCV2 has been shown to induce PMWS lesions in CDCD and SPF pigs, the presence of additional factors are required.

Function:
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents. Essential for the initial attachment to heparan sulfate moities and chondroitin sulfate B of the host cell surface proteoglycans. After attachment, the virus is internalized in a clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated pathway and traffics to the nucleus. The capsid protein binds and transports the viral genome and Rep across the nuclear envelope.    

猪圆环病毒Ⅱ型衣壳蛋白

hz-6063R PRMT6  组蛋白精氨酸甲基转移酶6抗体

hz-6064R PRSS8  丝氨酸蛋白酶8抗体

hz-6065R TCF3/E2A/E47  转录因子3抗体（螺旋环螺旋蛋白HE47）

hz-6066R phospho-TCF3/E47/E2A(Thr355)  磷酸化转录因子3抗体

hz-6068R LEPREL2  皮屑样蛋白2抗体

hz-6069R LLGL1/2  相似肿瘤抑制基因HUGL抗体

hz-6070R phospho-LLGL1 + LLGL2(Ser650+Ser654)  磷酸化相似肿瘤抑制基因HUGL抗体

hz-6071R LRP12  低密度脂蛋白受体相关蛋白12抗体（抑制肿瘤蛋白7）

hz-6072R MCC  大肠癌肿瘤突变蛋白抗体

hz-6073R MFSD2A  促进调解蛋白家族2A抗体

hz-6074R MIA2  黑色素瘤抑制活性蛋白2抗体

hz-6075R MTSS1  肿瘤转移抑制蛋白1

hz-6076R MTUS1/Angiotensin II Type 2 Receptor  血管紧张素Ⅱ2型受体相互作用蛋白抗体

hz-6077R NIT1  腈水解酶1抗体

hz-6078R RASSF3  Ras相关区域家族1A抗体

hz-6079R NPR2L/G21 protein  G21蛋白质抗体

hz-6080R XAB2/SYF1  XAB2蛋白抗体

hz-6081R PDGFRL  血小板源性生长因子受体β样蛋白抗体

hz-6082R PDSS2  抑癌蛋白DLP1抗体

hz-6083R PHAP1  蛋白磷酸酶2A抑制剂1抗体

hz-6084R POU6F2  转录因子RPF1抗体

hz-6085R PRKCDBP  蛋白激酶C delta结合蛋白抗体

hz-6086R Pinin  桥粒相关蛋白DRS抗体

hz-6088R RASAL1  RAS蛋白样激活剂1抗体

hz-6090R RBM5/LUCA15  肿瘤抑制基因LUCA15抗体

hz-6091R RERG  Ras相关雌激素调节生长抑制蛋白

hz-6092R RHOBTB1  Rho相关结构域BTB蛋白质1抗体

hz-6093R RIL  抑癌基因PDLIM4抗体

hz-6094R RIN1  RAS抑制蛋白1抗体

hz-6095R RND3/RHOE  Rho家族GTP酶3抗体

hz-6097R RSRC2  食道癌抑制生长蛋白抗体

hz-6098R PARG1/Rho GTPase activating protein 29  Rho GTP酶激活蛋白29抗体

hz-6099R SASH1  肿瘤抑制基因PEPE1抗体

hz-6100R SESN3  Sestrin3抗体