凋亡加强结构域蛋白14抗体

英文名称    CARD14    

中文名称    凋亡加强结构域蛋白14抗体    

别    名    Bcl10 interacting MAGUK protein 2; Bimp 2; Bimp2; CARD 14; CARD containing MAGUK 2 protein; CARD containing MAGUK protein 2; Card maguk protein 2; Carma 2; Carma2; Caspase recruitment domain containing protein 14; Caspase recruitment domain family member 14; Caspase recruitment domain protein 14; CAR14_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 凋亡加强结构域蛋白14抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    113kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from hu CARD14    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

凋亡加强结构域蛋白14抗体产品介绍    background:

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Function:
Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.    

凋亡加强结构域蛋白14抗体

hz-2473R BLAME/SLAMF8  BLAME抗体

hz-1341R Cdc2/CDK1  周期素依赖激酶1抗体

hz-3091R Phospho-cdc2 (Thr14)  磷酸化周期素依赖激酶2抗体

hz-3092R Phospho-cdc2 (Tyr15)  磷酸化周期素依赖激酶2抗体

hz-3481R Phospho-cdc2 (Thr161)  磷酸化周期素依赖激酶2抗体

hz-5247R Phospho-cdc2 (Ser39)  磷酸化周期素依赖激酶2抗体

hz-2758R Cdc25A  细胞分裂周期蛋白25抗体

hz-3093R Phospho-cdc25A (Thr506)  磷酸化细胞分裂周期蛋白25抗体

hz-3094R Phospho-cdc25A (Ser76)  磷酸化细胞分裂周期蛋白25抗体

hz-3095R Phospho-cdc25A (Ser178)  磷酸化细胞分裂周期蛋白25抗体

hz-3096R Phospho-cdc25C (Ser216)  磷酸化细胞分裂周期蛋白25C抗体

hz-3482R Phospho-cdc25C (Thr48)  磷酸化细胞分裂周期蛋白25C抗体

hz-5242R Phospho-cdc25A (Ser124)  磷酸化细胞分裂周期蛋白25抗体

hz-5261R Phospho-cdc25A (Ser177)  磷酸化细胞分裂周期蛋白25抗体

hz-5262R Phospho-cdc25A (Ser292)  磷酸化细胞分裂周期蛋白25抗体

hz-2417R CD335/NKp46/NCR1  细胞毒性受体NK-p46抗体

hz-2420R CD336/NKp44/NCR2  细胞毒性受体NK-p44抗体

hz-2418R CD337/NKp30/NCR3  细胞毒性受体NK-p30抗体

hz-2466R CD328/Siglec-7  唾液酸结合性免疫球蛋白样凝集素7抗体

hz-4094R Cdc25B  细胞分裂周期蛋白25B抗体

hz-2705R CD329/SIGLEC8  CD329抗体

hz-5243R phospho-Cdc25B (Ser323)  磷酸化细胞分裂周期蛋白25B抗体

hz-5244R phospho-Cdc25B (Ser186)  磷酸化细胞分裂周期蛋白25B抗体

hz-2681R KLRF1/NKp80  细胞毒性受体NK-p80抗体

hz-5245R phospho-Cdc25B (Ser353)  磷酸化细胞分裂周期蛋白25B抗体

hz-2706R SIGLEC10/SLG2  唾液酸结合性免疫球蛋白样凝集素抗体

hz-1390R Cdc6  细胞分裂周期蛋白6抗体

hz-1448R Jagged1/CD339  Jagged1/CD339抗体

hz-5148R Cdc7  细胞分裂周期蛋白7抗体

hz-4244R Jagged 2  Notch配体Jagged 2蛋白抗体

hz-3525R SIGLEC14  唾液酸结合性免疫球蛋白样凝集素14抗体

hz-5246R phospho-Cdc6 (Ser54)  磷酸化细胞分裂周期蛋白6抗体

hz-2707R SIGLEC11  唾液酸结合性免疫球蛋白样凝集素11抗体

hz-1392R CDC34/UBC3  细胞周期调控因子34

hz-4295R CDC40  细胞分裂周期同源蛋白40抗体