软骨衍生形态发生蛋白1/GDF 5抗体

英文名称    CDMP1    

中文名称    软骨衍生形态发生蛋白1/GDF 5抗体    

别    名    Cartilage derived morphogenetic protein 1; Cartilage-derived morphogenetic protein 1; CDMP-1; CDMP1; GDF-5; Gdf 5; GDF5_HUMAN; Growth differentiation factor 5; Growth/differentiation factor 5; LAP4; Radotermin.    

说 明 书    0.2ml      

研究领域    心血管  细胞生物  信号转导  干细胞  生长因子和激素  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 软骨衍生形态发生蛋白1/GDF 5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    55kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CDMP1/GDF5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

软骨衍生形态发生蛋白1/GDF 5抗体产品介绍    background:

Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet. Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet. Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.

Function:
Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B.    

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hz-9124RCOPS7A  信号转导蛋白亚基7A抗体

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hz-9128RCDCA7  细胞分裂周期相关蛋白

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hz-9133Rphospho-GPS1/CSN1(Ser474)  磷酸化G蛋白通路抑制蛋白1抗体

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hz-9135RASB17  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族17抗体

hz-9136RASB5  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族5抗体

hz-9137RZSWIM2  E3泛素蛋白连接酶ZSWIM2抗体

hz-9138RZSWIM3  ZSWIM3蛋白抗体

hz-9139RZNRF1  锌指/环指蛋白1抗体

hz-9140RZNRF2  锌指/环指蛋白2抗体

hz-9141RZNRF3  锌指蛋白3/环指蛋白3抗体

hz-9142RZNRF4  锌指/环指蛋白4抗体

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