磷酸化后期促进复合蛋白3抗体

英文名称    phospho-CDC27 (Ser426)    

中文名称    磷酸化后期促进复合蛋白3抗体    

别    名    CDC27 (phospho S426); CDC27 (phospho Ser426); p-CDC27 (phospho Ser426); ANAPC3; Anaphase Promoting Complex 3; Anaphase promoting complex protein 3; Anaphase Promoting Complex Subunit 3; Anaphase-promoting complex subunit 3; APC 3; APC3; APC-3; Cdc 27; Cdc27; Cdc-27; CDC27 homolog; CDC27_HUMAN; CDC27Hs; Cell division cycle 27; Cell division cycle protein 27 homolog; H NUC; H-NUC; HNUC; NUC2 homolog.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    细胞生物  免疫学  细胞周期蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化后期促进复合蛋白3抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    91kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from mouse CDC27 around the phosphorylation site of Ser426    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化后期促进复合蛋白3抗体产品介绍    background:

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] 

Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains    

磷酸化后期促进复合蛋白3抗体

hz-1954R BSEP/ABCB11  胆汁酸盐输出泵蛋白抗体

hz-2668R Bone sialoprotein  骨涎蛋白抗体

hz-0031R BTG2/TIS21  B细胞迁移基因2抗体

hz-2752R BTK/ATK  蛋白酪氨酸激酶ATK抗体

hz-3055R Phospho-Btk(Ser180)  磷酸化蛋白酪氨酸激酶ATK抗体

hz-3069R Phospho-BTK/BPK(Tyr223)  磷酸化蛋白酪氨酸激酶ATK抗体

hz-3820R BAP135/TFII I  蛋白酪氨酸激酶BAP135抗体

hz-4179R RAD9  细胞周期检查控制蛋白质抗体

hz-5642R phospho-RAD9(Ser272)  磷酸化细胞周期检查控制蛋白质抗体

hz-5643R phospho-RAD9(Ser277)  磷酸化细胞周期检查控制蛋白质抗体

hz-5654R phospho-RAD9(Ser328)  磷酸化细胞周期检查控制蛋白质抗体

hz-5655R phospho-RAD9(Ser336)  磷酸化细胞周期检查控制蛋白质抗体

hz-5656R phospho-RAD9(Ser375)  磷酸化细胞周期检查控制蛋白质抗体

hz-5657R phospho-RAD9(Ser380)  磷酸化细胞周期检查控制蛋白质抗体

hz-5658R phospho-RAD9(Ser387)  磷酸化细胞周期检查控制蛋白质抗体

hz-5659R phospho-RAD9(Tyr28)  磷酸化细胞周期检查控制蛋白质抗体

hz-5677R phospho-RAD51(Thr310)  磷酸化Rad51抗体

hz-5678R Phospho-RSK2(Ser369)  磷酸化核糖体S6激酶RSK2抗体

hz-0324R C5a  过敏毒素C5a（补体C5a）抗体

hz-2934R C3  过敏毒素C3（补体C3）抗体

hz-0367G human C3  补体C3抗体

hz-2673R C5b-9  末端补体复合物抗体

hz-3878R CQ028  多癌基因下调蛋白抗体

hz-0091R CA125/MUC16  卵巢癌抗原抗体

hz-1239R CA153/hzA/Mucin 1  乳腺癌相关抗原抗体

hz-1497R CA153/MUC1/KL-6  乳腺癌相关抗原抗体

hz-2776R CACH2/CaV1.2  L型钙通道蛋白抗体

hz-2781R CACNA1G/Cav3.1  电压依赖性钙通道Cav3.1抗体

hz-3930R CACNA1A/Cav2.1  电压依赖性钙通道Cav2.1抗体

hz-3932R CACH3/CaV1.3  L型钙通道蛋白a1亚型3抗体

hz-3933R CACH6/Cav2.3  L型钙通道蛋白a1亚型6抗体

hz-0043R DFF-40beta/CAD/CPAN  Caspase 激活的脱氧核糖核酸酶抗体