后期促进复合蛋白3抗体

英文名称    CDC27    

中文名称    后期促进复合蛋白3抗体    

别    名    ANAPC3; Anaphase Promoting Complex 3; Anaphase promoting complex protein 3; Anaphase Promoting Complex Subunit 3; Anaphase-promoting complex subunit 3; APC 3; APC3; APC-3; Cdc 27; Cdc27; Cdc-27; CDC27 homolog; CDC27_HUMAN; CDC27Hs; Cell division cycle 27; Cell division cycle protein 27 homolog; H NUC; H-NUC; HNUC; NUC2 homolog.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  细胞周期蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 后期促进复合蛋白3抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    90kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CDC27/ANAPC3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

后期促进复合蛋白3抗体产品介绍    background:

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.    

后期促进复合蛋白3抗体

hz-4222R PSME3/PA28 gamma  蛋白酶体激活因子PA28γ抗体

hz-4125R Pancreatic Lipase  胰脂肪酶抗体

hz-4183R RPH3AL  Ras相关GTP结合蛋白抗体

hz-5695R phospho-RPH3AL(Ser234)  磷酸化Ras相关GTP结合蛋白抗体

hz-4196R Prostaglandin E Receptor EP2  前列腺素E2受体2抗体

hz-2251R A Raf/ARAF  A-Raf抗体

hz-3005R phospho-A Raf(Ser214)  磷酸化A-Raf抗体

hz-3371R Phospho-A Raf(Ser299)  磷酸化A-Raf抗体

hz-3421R Phospho-A Raf(Tyr301/302)  磷酸化A-Raf抗体

hz-1089R B-Raf  B Raf抗体

hz-1703R c-Raf/Raf1  癌基因c-Raf抗体

hz-3013R phospho-B-Raf (Ser365)  磷酸化B-Raf抗体

hz-3373R phospho-B-Raf (Ser444)  磷酸化B-Raf抗体

hz-3374R phospho-B-Raf (Ser602)  磷酸化B-Raf抗体

hz-5232R phospho-B-Raf (Ser446)  磷酸化B-Raf抗体

hz-5233R phospho-B-Raf (Thr597)  磷酸化B-Raf抗体

hz-5224R phospho-B-Raf (Thr401)  磷酸化B-Raf抗体

hz-0802R BRCA1/BAP1  乳腺癌易感基因1抗体

hz-3051R Phospho-BAP1(Ser592)  磷酸化乳腺癌易感基因1抗体(人)

hz-3014R Phospho-BRCA1(Ser1524)  磷酸化乳腺癌易感基因1抗体

hz-5710R BRCC4/BRCC45  乳腺癌易感基因复合蛋白4抗体

hz-5221R Phospho-BRCA1(Ser1189)  磷酸化乳腺癌易感基因1抗体

hz-5222R Phospho-BRCA1(Ser1423)  磷酸化乳腺癌易感基因1抗体

hz-0803R BRCA1/BAP1  乳腺癌易感基因1抗体

hz-1210R BRCA2  乳腺癌易感基因2抗体

hz-0489R BrdU  溴脱氧尿苷抗体

hzm-0917M BrdU(A7)  溴脱氧尿苷单克隆抗体

hz-0917R BrdU  溴脱氧尿苷抗体

hz-3669R BRN3A  转录因子Brn3蛋白抗体Brn3α

hz-3668R Brs3/Bombesin Receptor 3  蛙皮素受体3抗体

hz-1408R SMARCA4/SNF2 beta/BRG1  抑癌基因SNF2β抗体

hz-1015R BRMS-1  乳腺癌转移抑制基因1抗体

hz-2229R Brucella  布氏杆菌菌体蛋白抗体

hz-0292R BSA/Bovine Serum Albumin  牛血清白蛋白抗体