英文名称 CD44v5
中文名称 CD44V5抗体
别 名 CD44 antigen; CD44 molecule; Heparan sulfate proteoglycan; PGP1; CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MGC10468; MIC4; hematopoietic cell E- and L-selectin ligand; chondroitin sulfate proteoglycan 8; cell surface glycoprotein CD44; GP90 lymphocyte homing/adhesion receptor; heparan sulfate proteoglycan; hyaluronate receptor; Hermes antigen; homing function and Indian blood group system; epican; phagocytic glycoprotein 1; extracellular matrix receptor III.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 细胞生物 细胞粘附分子 细胞表面分子 糖蛋白 淋巴细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,
产品应用 WB=1:100-500 ELISA=1:500-2000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 CD44V5抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 85kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD44v5
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD44V5抗体产品介绍 background:
CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Function:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
CD44V5抗体
hz-0527P CD10/CALLA (Neutral Endopeptidase) CD10抗原
hz-0354P ZCWCC1(Zinc finger CW-type coiled-coil domain protein 1) ZCWCC1抗原
hz-0579P CD105/Endoglin/TGF- Beta receptor CD105/转化生长因子β受体抗原
hz-1309P CD138/Syndecan-1 多配体蛋白聚糖1抗原
hz-1618P CD146/MCAM 黑色素瘤细胞粘附分子CD146抗原
hz-1383P ANPEN/CD13(Aminopeptidase N) 氨肽酶N抗原
hz-1192P CD14(cluster of differentiation antigen 14) CD14/内毒素受体抗原
hz-1297P CD28 CD28抗原
hz-1251P CD166/ALCAM(activated leukocyte celladhesion molecule) 活化白细胞粘附分子抗原
hz-1482P CD177/NB1 peptide 嗜中性粒细胞抗原CD177抗原
hz-0528P CD24 CD24抗原
hz-0512P CD2AP (CD2-associated protein) 白细胞分化抗原CD2AP
hz-2042P CD33 peptide(human) CD33抗原(人)
hz-1514P CD33/Siglec-3(mouse ret) CD33抗原(大、小鼠)
hz-2038P CD34 CD34抗原(细胞表面的唾液粘蛋白)
hz-0979P CD38(mouse, rat) CD38多肽(小鼠、大鼠)
hz-0980P CD38(human) CD38抗原(人)
hz-1100P CD36 CD36(多肽)
hz-1520P CD7 CD7抗原
hz-1286P CD40L(CD40 Ligand/TNFSF5/CD154) CD40L抗原
hz-0521P CD44 CD44抗原 (多肽抗原)
Y-0206 Argireline peptide 抗皱寡肽-1/六胜肽-3/阿基瑞林/乙酰六胜肽-3
Y-0207 GHRP-2 Acetate peptide(Growth hormone-releasing peptides 2) 醋酸促生长激素释放肽2
Y-0208 GHRP-6 Acetate peptide(Growth hormone-releasing peptides 6) 醋酸促生长激素释放肽6
Y-0209 Matrixyl Acetate 五胜肽/美容肽—M肽
Y-0210 MT-II(Melanotan II Acetate) 醋酸美拉诺坦II
Y-0211 Pentapeptide-3/Leuphasyl 五胜肽
Y-0212 PT141(Brhzelanotide PT-141) 雌性激素肽
hz-0522P CD45 CD45(白细胞共同抗原)
hz-1539P CD46/MCP(mhzbrane cofactor protein)rat, mouse 膜辅蛋白/内源性辅助因子活性蛋白抗原
hz-1113P CD5 CD5 多肽抗原
hz-1258P ICAM-2/CD102(intercellular adhesion molecules-2) 细胞间粘附分子-2抗原
hz-0805P CD56/NCAM1(Neural Cell Adhesion Molecule 1) 神经细胞粘附分子1抗原
hz-1036P CD62L (ELAM-1/L-Selectin ) L选择素抗原
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