英文名称 CD155
中文名称 脊髓灰质炎病毒受体抗体
别 名 Poliovirus receptor; poliovirus receptor isoform alpha; CD155; FLJ25946; HVED; Necl-5; NECL5; PVS; TAGE4; Taa1; CD155 antigen; Nectin like 5; Nectin like protein 5; Ortholog of mouse Tage4; PVR; PVR_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 神经生物学 细胞膜受体 细菌及病毒
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 脊髓灰质炎病毒受体抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞膜 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD155
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
脊髓灰质炎病毒受体抗体产品介绍 background:
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function:
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.
脊髓灰质炎病毒受体抗体
hz-0210P Tubulin- Beta 微管蛋白(抗原)
hz-0452P NAIF1 protein( CB12-327) 核凋亡诱导因子蛋白1(多肽)
hz-1500P cath-B/CB(Cathepsin B) 组织蛋白酶B抗原
hz-1508P cath-L/CL peptide 组织蛋白酶L抗原
hz-1134P CBFA1/RUNX2 (Runt-related Transcription Factor 2) 成骨特异性转录因子(多肽)
hz-1397P CBP(CREB-binding protein) CREB结合蛋白抗原
hz-1421P CBX3/HP1 gamma 染色盒同源物3抗原
hz-0955P CBX5(Chromobox Homolog 5) CBX5(多肽)
hz-1487P CC16(Clara cell protein 16) peptide 克拉拉细胞蛋白(Clara细胞分泌蛋白)抗原
hz-0562P CCR-2/5(CC chhzokine receptor 2/5) CC趋化因子受体2/5抗原
hz-2450P CCL1/TCA3/I-309 嗜酸粒细胞趋化蛋白CCL1抗原
hz-1324P CCL5/RANTES(regulated on activation normal T cell expressed and secreted) 活化T细胞表达和分泌的调节因子抗原
hz-2475P CCL4/MIP-1 Beta(Macrophage Inflammatory Protein 1 beta) 巨噬细胞炎性蛋白1β抗原
hz-1268P MIP3 Alpha/CCL20(Macrophage inflammatory ptotein 3 alpha) 巨噬细胞炎性蛋白3α抗原
hz-2478P CCL12/MCP-5(C-C motif chhzokine 12) 单核细胞趋化蛋白5抗原
hz-2479P CCL14/HCC-1(C-C motif chhzokine 14) 嗜酸粒细胞趋化蛋白14抗原
hz-1761P ABCD-1/CCL22 嗜酸粒细胞趋化蛋白22抗原
hz-2454P MIP-3 beta/ELC/CCL19(Macrophage Inflammatory Protein 3 Beta) 巨噬细胞炎性蛋白19抗原
hz-1762P CCL26(Eotaxin 3) 嗜酸粒细胞趋化蛋白3抗原
hz-1169P CCR-1(CC chhzokine receptor 1) 细胞表面趋化因子受体1抗原
hz-1167P CCR-3(CC chhzokine receptor 3) CC趋化因子受体3抗原
hz-1671P CCR-2A(C-C Chhzokine receptor 2A) 细胞表面趋化因子受体2A抗原
hz-1168P CCR-4(C-C chhzokine receptor 4) 细胞表面趋化因子受体4抗原
hz-1542P CCR-6/CD196 peptide 细胞表面趋化因子受体6抗原
hz-1628P CXCR6(CXC-chhzokine receptor 6) peptide 细胞表面趋化因子受体6抗原
hz-1305P CCR-7(CC chhzokine receptor 7) CC趋化因子受体7(多肽)
hz-1502P CXCL10/IP-10 CXCL10趋化因子10/干扰素诱导蛋白10抗原
hz-0279P VEGF(Vascular endothelial growth factor) 血管内皮生长因子(多肽抗原)
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