您好,欢迎访问仪器信息网
注册
上海通蔚实业有限公司

关注

已关注

已认证

粉丝量 0

当前位置: 上海通蔚 > 抗体/抗原 > 磷酸化腺泡Acinus蛋白抗体

磷酸化腺泡Acinus蛋白抗体

供货周期: 一周
品牌: EterLife
规格: 0.1ml/100μg 、0.2ml/200μg
货号: TE-KT-0178
CAS号: 详见产品说明书
报价: 面议
留言咨询
产品介绍

磷酸化腺泡Acinus蛋白抗体

〖别名〗Acinus (phospho S1180); Acinus (phospho Ser1180); Acinus (phospho-S1180); Acinus (phospho-Ser1180); p-Acinus (Ser1180); ACIN 1; ACIN1; ACINU_HUMAN; Acinus; ACN; Apoptotic chromatin condensation inducer 1; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; fSAP152; functional spliceosome-associated protein 152; KIAA0670. 

〖浓度〗1mg/1ml 

〖规格〗0.1ml/100μg   

〖抗体来源〗Rabbit  

〖克隆类型〗polyclonal 

〖交叉反应〗Human, Mouse, Rat, Dog, Pig, Cow, Horse  

〖产品类型〗磷酸化腺泡Acinus蛋白抗体一抗  磷酸化抗体  

〖研究领域〗细胞生物 神经生物学 信号转导 细胞凋亡 转录调节因子  

〖蛋白分子量〗predicted molecular weight: 148kDa 

〖性状〗Lyophilized or Liquid 

〖免疫原〗KLH conjugated Synthesised phosphopeptide derived from human Acinus around the phosphorylation site of Ser1180 

〖亚型〗IgG 

〖纯化方法〗affinity purified by Protein A 

〖储存液〗0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

〖产品应用〗IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

〖产品介绍〗Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), Acinus S (583 amino acids) and Acinus S' (614 amino acids)

Function : Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells. 

Subunit : Found in a mRNA splicing-dependent exon junction complex (EJC), at least composed of ACIN1, CASC3, EIF4A3, MAGOH, PNN, RBM8A, RNPS1, SAP18 and ALYREF/THOC4. Forms heterodimers with RNPS1. Found in a heterotrimeric complex with ACIN1, RNPS1 and SAP18. Interacts with API5. Interacts with SRPK2 in a phosphorylation-dependent manner.

Subcellular Location : Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Note=Phosphorylation on Ser-1180 by SRPK2 redistributes it from the nuclear speckles to the nucleoplasm.

Tissue Specificity : Ubiquitous. The Ser-1180 phosphorylated form (by SRPK2) is highly expressed and phosphorylated in patients with myeloid hematologic malignancies.

Post-translational modifications : Phosphorylation on Ser-1180 by SRPK2 up-regulates its stimulatory effect on cyclin A1. 

Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.

Similarity : Contains 1 SAP domain.

Database links : UniProtKB/Swiss-Prot: Q9UKV3.2

本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的磷酸化腺泡Acinus蛋白抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。

我们还可以为客户提供产品说明书。磷酸化腺泡Acinus蛋白抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。

Ab-(001)-08596 Measles virus protein(Plant2 derived measles virus hemagglutinin protein) 麻疹病毒红血球凝集素蛋白多肽 ,英文名: Measles ,规格: 0.5mg

Ab-(001)-08597 HMGB1 (High Mobility Group Box protein 1) 高迁移率族蛋白-1(抗原) ,英文名: HMGB1 ,规格: 0.5mg

Ab-(001)-08598 HSL(hormone-sensitive lipase) 荷尔蒙敏感脂肪酸(抗原) ,英文名: HSL ,规格: 0.5mg

Ab-(001)-08599 HSP-27(Heat Shock Protein 27) 热休克蛋白-27(抗原) ,英文名: HSP-27 ,规格: 0.5mg

Ab-(001)-08600 HSP-90Alpha(Heat Shock Protein 90Alpha ) 热休克蛋白90α(抗原) ,英文名: HSP-90Alpha ,规格: 0.5mg

Ab-(001)-08601 HSP-90 Beta (heat sock protein-90 Beta) 热休克蛋白-90β (抗原) ,英文名: HSP-90 ,规格: 0.5mg

Ab-(001)-08602 IASPP(inhibitory member of the ASPP family) 肿瘤细胞凋亡ASPP家族的另一个成员(抗原) ,英文名: IASPP ,规格: 0.5mg

Ab-(001)-08603 CD54 ICAM-1 (Intercellular dhesion molecule 1; CD54 Anti-gen;) 细胞间粘附分子-1(多肽抗原) ,英文名: CD54 ,规格: 0.5mg

Ab-(001)-08604 IL-1 Beta(Interleukin-1 Beta) 白介素1β(白细胞介素-1β)(多肽抗原) ,英文名: IL-1 ,规格: 0.5mg

Ab-(001)-08605 IL1RAPL1 (Interleukin 1 receptor accessory protein-like 1) 白介素受体相关蛋白样1前体蛋白(抗原) ,英文名: IL1RAPL1 ,规格: 0.5mg

Ab-(001)-08606 IL-6(Interleukin-6) 白介素6(白细胞介素-6)(多肽抗原) ,英文名: IL-6 ,规格: 0.5mg

Ab-(001)-08607 IL-10(Interleukin-10) 白介素10(白细胞介素-10)(抗原) ,英文名: IL-10 ,规格: 0.5mg

Ab-(001)-08608 IL-8 白介素8(白细胞介素-8)(抗原) ,英文名: IL-8 ,规格: 0.5mg

Ab-(001)-08609 Insulin Receptor(ISR) 胰岛素受体(抗原) ,英文名: Insulin ,规格: 0.5mg

Ab-(001)-08610 Integrin Alpha 4/ITGA4(Integrin alpha 4) 整合素-α(抗原) ,英文名: Integrin ,规格: 0.5ml

Ab-(001)-08611 LDL-R(Low-density lipoprotein receptor precursor) 低密度脂蛋白受体(抗原) ,英文名: LDL-R ,规格: 0.5mg

Ab-(001)-08612 Ki-67 Anti-gen Ki-67 Antigen(抗原) ,英文名: Ki-67 ,规格: 0.5mg

Ab-(001)-08613 Kiss-1(Metastasis-suppressor KiSS-1 precursor) 肿瘤转移抑制基因(抗原) ,英文名: Kiss-1 ,规格: 0.5mg

Ab-(001)-08614 Snake poison Protein 蛇毒蛋白 ,英文名: Snake ,规格: 0.5mg

Ab-(001)-08615 Snake poison Protein 蛇毒蛋白 ,英文名: Snake ,规格: 1mg

Ab-(001)-08616 Batroxobin Protein 蛇毒巴曲酶全蛋白 ,英文名: Batroxobin ,规格: 1mg

Ab-(001)-08617 Leptin 瘦素(抗原) ,英文名: Leptin ,规格: 0.5mg

Ab-(001)-08618 Lpin1 protein Lpin1 protein(抗原) ,英文名: Lpin1 ,规格: 0.5mg

Ab-(001)-08619 Lumbrokinase 蚯蚓纤溶酶(蚓激酶抗原) ,英文名: Lumbrokinase ,规格: 0.5mg

Ab-(001)-08620 Livin (Inhibitors of apoptosis proterins Livin) 一种新的凋亡抑制蛋白(抗原) ,英文名: Livin ,规格: 0.5mg

Ab-(001)-08621 p38 MAPK/MKK3/MAPKK14 丝裂原活化蛋白激酶p38(抗原) ,英文名: p38 ,规格: 0.5mg

Ab-(001)-08622 Metal ion transporter 拟南介金属离子转运蛋白(抗原) ,英文名: Metal ,规格: 0.5mg

Ab-(001)-08623 MADCAM-1 黏膜选址素(抗原) ,英文名: MADCAM-1 ,规格: 0.5mg

Ab-(001)-08624 MAG-a/b (Myelin associated glycoprotein; L / S -MAG;) 髓鞘相关糖蛋白a/b(抗原) ,英文名: MAG-a/b ,规格: 0.5mg

Ab-(001)-08625 MAG (Myelin associated glycoprotein; L-MAG;MAG-a ) 髓鞘相关糖蛋白(抗原) ,英文名: MAG ,规格: 0.5mg

Ab-(001)-08626 MAG-a (Myelin associated glycoprotein; L-MAG; ) 髓鞘相关糖蛋白-a(抗原) ,英文名: MAG-a ,规格: 0.5mg

Ab-(001)-08627 MMP-1(Mous ematrix metalloproteinases-1) 基质金属蛋白酶-1(小鼠抗原) ,英文名: MMP-1 ,规格: 0.5mg

Ab-(001)-08628 midnolin isoform Protein 1 中脑核仁蛋白1(抗原) ,英文名: midnolin ,规格: 0.5mg

Ab-(001)-08629 midnolin isoform Protein 2 中脑核仁蛋白2(抗原) ,英文名: midnolin ,规格: 0.5mg

Ab-(001)-08630 MICA(MHC class I polypeptide-related sequence A) 一种细胞应激分子抗原 ,英文名: MICA ,规格: 0.5mg

Ab-(001)-08631 MRP3(Multidrug Resistanec-Associated Protein 3) 多药耐药相关蛋白3(抗原) ,英文名: MRP3 ,规格: 0.5mg

Ab-(001)-08632 MRP1(Multidrug Resistanec-Associated Protein 1) 多药耐药相关蛋白1(抗原) ,英文名: MRP1 ,规格: 0.5mg

Ab-(001)-08633 LRP/MVP (Lung resistance related protein) 肺耐药相关蛋白(抗原) ,英文名: LRP/MVP ,规格: 0.5mg

Ab-(001)-08634 MSLN(mesothelin) 间皮素(多肽抗原) ,英文名: MSLN ,规格: 0.5mg

Ab-(001)-08635 MSH2 (mutS homolog 2) MSH2抗原 ,英文名: MSH2 磷酸化腺泡Acinus蛋白抗体规格: 0.5mg

Ab-(001)-08636 NKR(Neuromedin B Receptor) 神经激肽B受体(抗原) ,英文名: NKR ,规格: 0.5mg

Ab-(001)-08637 NF-L(Neurofilament triplet L) 低分子量神经丝蛋白(抗原) ,英文名: NF-L ,规格: 0.5mg


工商信息

企业名称

上海通蔚实业有限公司

企业信息已认证

企业类型

信用代码

310116003070684

成立日期

2014-04-16

注册资本

10

经营范围

联系我们
磷酸化腺泡Acinus蛋白抗体由上海通蔚实业有限公司为您提供,货号TE-KT-0178,规格:0.1ml/100μg 、0.2ml/200μg,CAS号:详见产品说明书,如您想了解更多关于磷酸化腺泡Acinus蛋白抗体价格、磷酸化腺泡Acinus蛋白抗体结构式、批发、用途等信息,欢迎咨询。除供应磷酸化腺泡Acinus蛋白抗体外,还可为您提供5-溴-4-氯-3-吲哚半乳糖苷、育亨酸、甲氧醉椒素等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海通蔚客户服务电话,售前、售后均可联系。

上海通蔚实业有限公司

沟通底价

提交后,商家将派代表为您专人服务

获取验证码

{{maxedution}}s后重新发送

获取多家报价,选型效率提升30%
提交留言
点击提交代表您同意 《用户服务协议》 《隐私政策》 且同意关注厂商展位
联系方式:

公司名称: 上海通蔚实业有限公司

公司地址: 上海市金山区枫泾镇环东一路65弄2号3463室 联系人: 戴霍玲 邮编: 201501

仪器信息网APP

展位手机站