ALKB蛋白抗体
〖别名〗ABH; ABH1; alkB; AlkB, alkylation repair homolog 1 (E. coli); ALKB1_HUMAN; ALKBH; ALKBH1; Alkylated DNA repair protein alkB homolog 1; Alkylation repair homolog 1; Alkylation repair, alkB homolog; Alpha-ketoglutarate-dependent dioxygenase ABH1; DNA lyase ABH1; hABH.
〖浓度〗1mg/1ml
〖规格〗0.2ml/200μg
〖抗体来源〗ALKB蛋白抗体Rabbit
〖克隆类型〗polyclonal
〖交叉反应〗Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
〖产品类型〗一抗
〖研究领域〗肿瘤 神经生物学 表观遗传学
〖蛋白分子量〗predicted molecular weight: 44kDa
〖性状〗Lyophilized or Liquid
〖免疫原〗KLH conjugated synthetic peptide derived from human ABH1/ALKB
〖亚型〗IgG
〖纯化方法〗affinity purified by Protein A
〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
〖产品应用〗WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
〖产品介绍〗ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
Function : Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.
Subunit : Monomer. Interacts with DNAJB6 (By similarity).
Subcellular Location : Mitochondrion. Nucleus. Mainly localizes in euchromatin, largely excluded from heterochromatin and nucleoli.
Tissue Specificity : Ubiquitous.
Similarity : Belongs to the alkB family.
Contains 1 Fe2OG dioxygenase domain.
Database links : UniProtKB/Swiss-Prot: Q13686.2
本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的ALKB蛋白抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。
我们还可以为客户提供产品说明书。ALKB蛋白抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。
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Ab-(001)-04627 Anti-BIRC5/FITC 荧光素标记细胞凋亡抑制因子5抗体IgG ,英文名: Anti-BIRC5/FITC ,规格: 0.2ml
Ab-(001)-04628 Anti-CD203c/FITC 荧光素标记CD203c抗体IgG ,英文名: Anti-CD203c/FITC ,规格: 0.2ml
Ab-(001)-04629 Anti-CD203c/RBITC 红色荧光素罗丹明(RBITC)标记抗CD203c抗体IgG ,英文名: Anti-CD203c/RBITC ,规格: 0.2ml
Ab-(001)-04630 Anti-BNP/HRP 辣根过氧化物酶标记兔抗人脑钠素抗体IgG ,英文名: Anti-BNP/HRP ,规格: 0.2ml
Ab-(001)-04631 Anti-CD31/HRP 辣根过氧化物酶标记CD31抗体IgG ,英文名: Anti-CD31/HRP ,规格: 0.2ml
Ab-(001)-04632 Anti-BK channel/FITC 荧光素标记BK通道蛋白抗体IgG ,英文名: Anti-BK ,规格: 0.2ml
Ab-(001)-04633 Anti-BKCa channels/FITC 荧光素标记钙激活钾通道蛋白抗体IgG ,英文名: Anti-BKCa ,规格: 0.2ml
Ab-(001)-04634 Anti-Bmi1/PCGF4/FITC 荧光素标记组蛋白相关Bmi1抗体IgG ,英文名: Anti-Bmi1/PCGF4/FITC ,规格: 0.2ml
Ab-(001)-04635 Anti-BLAME/SLAMF8/FITC 荧光素标记BLAME抗体IgG ,英文名: Anti-BLAME/SLAMF8/FITC ,规格: 0.2ml
Ab-(001)-04636 Anti-BLNK/B-cell linker protein /FITC 荧光素标记兔抗人、大、小鼠T淋巴细胞连接蛋白抗体IgG ,英文名: Anti-BLNK/B-cell ,规格: 0.2ml
Ab-(001)-04637 Anti-Phospho-BLNK(p-Tyr96) /FITC 荧光素标记兔抗人磷酸化T淋巴细胞连接蛋白抗体IgG ,英文名: Anti-Phospho-BLNK ,规格: 0.2ml
Ab-(001)-04638 Anti-BMP2/FITC 荧光素标记骨形态发生蛋白-2抗体IgG ,英文名: Anti-BMP2/FITC ,规格: 0.2ml
Ab-(001)-04639 Anti-BMP4/FITC 荧光素标记骨形态发生蛋白4抗体IgG ,英文名: Anti-BMP4/FITC ,规格: 0.2ml
Ab-(001)-04640 Anti-BMP6/FITC 荧光素标记骨形态发生蛋白6抗体IgG ,英文名: Anti-BMP6/FITC ,规格: 0.2ml
Ab-(001)-04641 Anti-BMP-7/FITC 荧光素标记骨形态发生蛋白-7抗体IgG ,英文名: Anti-BMP-7/FITC ,规格: 0.2ml
Ab-(001)-04642 Anti-BMP8/FITC 荧光素标记骨形态发生蛋白8抗体IgG ,英文名: Anti-BMP8/FITC ,规格: 0.2ml
Ab-(001)-04643 Anti-BMPR-1A/FITC 荧光素标记骨成型蛋白受体1A抗体IgG ,英文名: Anti-BMPR-1A/FITC ,规格: 0.2ml
Ab-(001)-04644 Anti-BNP/FITC 荧光素标记脑钠素抗体IgG ,英文名: Anti-BNP/FITC ,规格: 0.2ml
Ab-(001)-04645 Anti-BNP/FITC 荧光素标记脑钠素抗体IgG ,英文名: Anti-BNP/FITC ,规格: 0.2ml
Ab-(001)-04646 Anti-BRN3A /FITC 荧光素标记转录因子Brn3蛋白抗体IgG ,英文名: Anti-BRN3A ,规格: 0.2ml
Ab-(001)-04647 Anti-BOb-1/FITC 荧光素标记B细胞特异性转录因子抗体IgG ,英文名: Anti-BOb-1/FITC ,规格: 0.2ml
Ab-(001)-04648 Anti-BRAF/FITC 荧光素标记黑素瘤相关蛋白抗体IgG ,英文名: Anti-BRAF/FITC ,规格: 0.2ml
Ab-(001)-04649 Anti-B Raf(phospho S365) /FITC 荧光素标记兔抗人、大、小鼠磷酸化B-Raf抗体IgG ,英文名: Anti-B ,规格: 0.2ml
Ab-(001)-04650 Anti-phospho-B-Raf (Ser445)/FITC 荧光素标记磷酸化B-Raf抗体IgG ,英文名: Anti-phospho-B-Raf ,规格: 0.2ml
Ab-(001)-04651 Anti-phospho-B-Raf (Ser601) /FITC 荧光素标记磷酸化B-Raf抗体IgG ,英文名: Anti-phospho-B-Raf ,规格: 0.2ml
Ab-(001)-04652 Anti-BRCA1(human)/FITC 荧光素标记乳腺癌易感基因1抗体(人)IgG ,英文名: Anti-BRCA1 ,规格: 0.2ml
Ab-(001)-04653 Anti-BRCA1(mouse rat)/FITC 荧光素标记乳腺癌易感基因1抗体(小鼠 大鼠)IgG ,英文名: Anti-BRCA1 ,规格: 0.2ml
Ab-(001)-04654 Anti-BRCA1(Phospho Ser1524) /FITC 荧光素标记兔抗人、大、小鼠磷酸化乳腺癌易感基因1抗体IgG ,英文名: Anti-BRCA1 ,规格: 0.2ml
Ab-(001)-04655 Anti-BRCA2/FITC 荧光素标记乳腺癌易感基因2抗体IgG ,英文名: Anti-BRCA2/FITC ,规格: 0.2ml
Ab-(001)-04656 Anti-BrdU/FITC(Bromodeoxyuridine) 荧光素标记兔抗溴脱氧尿苷抗体IgG ,英文名: Anti-BrdU/FITC ,规格: 0.2ml
Ab-(001)-04657 Anti-BrdU/FITC 荧光素标记溴脱氧尿苷抗体IgG ,英文名: Anti-BrdU/FITC ,规格: 0.2ml
Ab-(001)-04658 Anti-SMARCA4/SNF2 beta/FITC 荧光素标记抑癌基因SNF2β抗体IgG ,英文名: Anti-SMARCA4/SNF2 ,规格: 0.2ml
Ab-(001)-04659 Anti-BRMS-1/FITC 荧光素标记乳腺癌转移抑制基因1抗体IgG ,英文名: Anti-BRMS-1/FITC ,规格: 0.2ml
Ab-(001)-04660 Anti-BTG2/TIS21/FITC 荧光素标记B细胞迁移基因2抗体IgG ,英文名: Anti-BTG2/TIS21/FITC ,规格: 0.2ml
Ab-(001)-04661 Anti-Brucella/FITC 荧光素标记抗布鲁氏菌抗体IgG ,英文名: Anti-Brucella/FITC ,规格: 0.2ml
Ab-(001)-04662 Anti-Brucella/HRP 辣根过氧化物酶标记抗布鲁氏菌抗体IgG ,英文名: Anti-Brucella/HRP ,规格: 0.2ml
Ab-(001)-04663 Anti-Brucella/Biotin 生物素标记抗布鲁氏菌抗体IgG ,英文名: Anti-Brucella/Biotin ,规格: 0.2ml
Ab-(001)-04664 Anti-BSEP/FITC 荧光素标记胆汁酸盐输出泵蛋白抗体IgG ,英文名: Anti-BSEP/FITC ,规格: 0.2ml
Ab-(001)-04665 Anti-BSP/FITC 荧光素标记骨涎蛋白抗体IgG ,英文名: Anti-BSP/FITC ,规格: 0.2ml
Ab-(001)-04666 Goat Anti-human C3/FITC 荧光素标记羊抗人补体C3 IgG ,英文名: Goat ,规格: 0.2ml
Ab-(001)-04667 Anti-C5a/FITC 荧光素标记过敏毒素C5a(补体C5a)抗体IgG ,英文名: Anti-C5a/FITC ,规格: 0.2ml
Ab-(001)-04668 Anti-C5b-9/TCC/FITC 荧光素标记末端补体复合物C5b-9抗体IgG ,英文名: Anti-C5b-9/TCC/FITC ,ALKB蛋白抗体规格: 0.2ml
Ab-(001)-04669 Anti-CA125/FITC 荧光素标记卵巢癌抗原抗体IgG ,英文名: Anti-CA125/FITC ,规格: 0.2ml
Ab-(001)-04670 Anti-CA15-3/FITC 荧光素标记乳腺癌相关抗原抗体IgG ,英文名: Anti-CA15-3/FITC ,规格: 0.2ml
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上海通蔚实业有限公司
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成立日期
2014-04-16
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