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当前位置: 上海通蔚 > 抗体/抗原 > 磷酸化活化复制因子2抗体

磷酸化活化复制因子2抗体

供货周期: 一周
品牌: EterLife
规格: 0.1ml/100μg 、0.2ml/200μg
货号: TE-KT-0079
CAS号: 详见产品说明书
报价: 面议
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产品介绍

磷酸化活化复制因子2抗体

〖别名〗ATF2 (phospho S480); p-ATF2 (phospho S480); p-ATF2 (phospho Ser480); ATF2(Phospho-Ser480); CREB 2; HB 16; Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive; ATF2_HUMAN. 

〖浓度〗1mg/1ml 

〖规格〗0.1ml/100μg   

〖抗体来源〗磷酸化活化复制因子2抗体Rabbit  

〖克隆类型〗polyclonal 

〖交叉反应〗Human, Mouse   

〖产品类型〗一抗  磷酸化抗体  

〖研究领域〗细胞生物 神经生物学 转运蛋白 表观遗传学  

〖蛋白分子量〗predicted molecular weight: 45kDa 

〖性状〗Lyophilized or Liquid 

〖免疫原〗KLH conjugated synthesised phosphopeptide derived from human ATF2 around the phosphorylation site of Ser480 

〖亚型〗IgG 

〖纯化方法〗affinity purified by Protein A 

〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

〖产品应用〗WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

〖产品介绍〗ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.

Function : Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.

Subunit : Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.

Subcellular Location : Nucleus.

Tissue Specificity : Abundant expression seen in the brain.

Post-translational modifications : Phosphorylation of Thr-69 and Thr-71 by MAPK14 causes increased transcriptional activity. Also phosphorylated and activated by JNK.

Similarity : Belongs to the bZIP family. ATF subfamily.

Contains 1 bZIP domain.

Contains 1 C2H2-type zinc finger.

Database links : UniProtKB/Swiss-Prot: P15336.4

本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的磷酸化活化复制因子2抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。

我们还可以为客户提供产品说明书。磷酸化活化复制因子2抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。

Ab-(001)-04009 Anti-Phospho-TAK1 (Thr184) 磷酸化转化生长因子β活化激酶1 ,英文名: Anti-Phospho-TAK1 ,规格: 0.1ml

Ab-(001)-04010 Anti-Phospho-TAK1 (Thr187) 磷酸化转化生长因子β活化激酶1 ,英文名: Anti-Phospho-TAK1 ,规格: 0.1ml

Ab-(001)-04011 Anti-Phospho-TAK1 (Thr184/187) 磷酸化转化生长因子β活化激酶1 ,英文名: Anti-Phospho-TAK1 ,规格: 0.1ml

Ab-(001)-04012 Anti-Tap1/ABCB2 ATP结合转运因子1抗体 ,英文名: Anti-Tap1/ABCB2 ,规格: 0.2ml

Ab-(001)-04013 Anti-Tanis/SELS(Selenoprotein S) 炎症负调控因子蛋白抗体 ,英文名: Anti-Tanis/SELS ,规格: 0.2ml

Ab-(001)-04014 Anti-TANK TANK抗体 ,英文名: Anti-TANK ,规格: 0.1ml

Ab-(001)-04015 Anti-Phospho-TBK1/NAK (Ser172) NF-κB活化激酶抗体 ,英文名: Anti-Phospho-TBK1/NAK ,规格: 0.1ml

Ab-(001)-04016 Anti-Tat 细胞酪氨酸转氨酶抗体 ,英文名: Anti-Tat ,规格: 0.2ml

Ab-(001)-04017 Anti-Tau protein 微管相关蛋白抗体 ,英文名: Anti-Tau ,规格: 0.1ml

Ab-(001)-04018 Anti-TRH 促甲状腺素释放激素抗体 ,英文名: Anti-TRH ,规格: 0.2ml

Ab-(001)-04019 Anti-Tau protein 微管相关蛋白抗体 ,英文名: Anti-Tau ,规格: 0.1ml

Ab-(001)-04020 Anti-phospho-Tau protein (Thr489) 磷酸化微管相关蛋白抗体 ,英文名: Anti-phospho-Tau ,规格: 0.1ml

Ab-(001)-04021 Anti-phospho-Tau protein (Ser396) 磷酸化微管相关蛋白抗体 ,英文名: Anti-phospho-Tau ,规格: 0.1ml

Ab-(001)-04022 Anti-phospho-Tau protein (Ser422) 磷酸化微管相关蛋白抗体 ,英文名: Anti-phospho-Tau ,规格: 0.1ml

Ab-(001)-04023 Anti-MAP2 微管相关蛋白2抗体 ,英文名: Anti-MAP2 ,规格: 0.1ml

Ab-(001)-04024 Anti-Phospho-MAP2 (Ser136) 磷酸化微管相关蛋白2抗体 ,英文名: Anti-Phospho-MAP2 ,规格: 0.1ml

Ab-(001)-04025 Anti-Phospho-MAP2 (Thr1620/1623) 磷酸化微管相关蛋白2抗体 ,英文名: Anti-Phospho-MAP2 ,规格: 0.1ml

Ab-(001)-04026 Anti-MAP1A 微管相关蛋白1A抗体 ,英文名: Anti-MAP1A ,规格: 0.1ml

Ab-(001)-04027 Anti-Talin 踝蛋白抗体 ,英文名: Anti-Talin ,规格: 0.1ml

Ab-(001)-04028 Anti-Phospho-Talin (Ser425) 磷酸化踝蛋白抗体 ,英文名: Anti-Phospho-Talin ,规格: 0.1ml

Ab-(001)-04029 Anti-TBX2/T-box2 新型抑癌基因抗体 ,英文名: Anti-TBX2/T-box2 ,规格: 0.1ml

Ab-(001)-04030 Anti-TBX3 转录因子Tbx3抗体 ,英文名: Anti-TBX3 ,规格: 0.2ml

Ab-(001)-04031 Anti-Tbx21/T-bet T细胞介导的转录调节因子Tbx21抗体 ,英文名: Anti-Tbx21/T-bet ,规格: 0.1ml

Ab-(001)-04032 Anti-TBX18 转录因子Tbx18抗体 ,英文名: Anti-TBX18 ,规格: 0.2ml

Ab-(001)-04033 Anti-TCF7L2 转录因子7类似物2抗体 ,英文名: Anti-TCF7L2 ,规格: 0.1ml

Ab-(001)-04034 Anti-TCTP 翻译控制肿瘤蛋白抗体 ,英文名: Anti-TCTP ,规格: 0.2ml

Ab-(001)-04035 Anti-Phospho-TCTP (Ser46) 磷酸化翻译控制肿瘤蛋白抗体 ,英文名: Anti-Phospho-TCTP ,规格: 0.1ml

Ab-(001)-04036 Anti-TDP-43 Tar DNA 结合蛋白43抗体 ,英文名: Anti-TDP-43 ,规格: 0.1ml

Ab-(001)-04037 Anti-PHLDA1/TDAG51 T淋巴细胞凋亡相关蛋白TDAG51抗体 ,英文名: Anti-PHLDA1/TDAG51 ,规格: 0.2ml

Ab-(001)-04038 Anti-TEM 1/CD248 内涎蛋白/内皮唾液酸蛋白抗体 ,英文名: Anti-TEM ,规格: 0.2ml

Ab-(001)-04039 Anti-TEM8 肿瘤血管内皮标志物8抗体 ,英文名: Anti-TEM8 ,规格: 0.2ml

Ab-(001)-04040 Anti-TERT 端粒酶逆转录酶抗体 ,英文名: Anti-TERT ,规格: 0.1ml

Ab-(001)-04041 Anti-TETRODOTOXIN ( TTX ) 河豚毒素抗体 ,英文名: Anti-TETRODOTOXIN ,规格: 0.1ml

Ab-(001)-04042 Anti-TP-1/TEP1 端粒酶相关蛋白1抗体 ,英文名: Anti-TP-1/TEP1 ,规格: 0.2ml

Ab-(001)-04043 Anti-Tetraspan5 四分子交联体5抗体 ,英文名: Anti-Tetraspan5 ,规格: 0.1ml

Ab-(001)-04044 Anti-TFF2 三叶肽因子2抗体 ,英文名: Anti-TFF2 ,规格: 0.1ml

Ab-(001)-04045 Anti-TFF3 三叶肽因子3抗体 ,英文名: Anti-TFF3 ,规格: 0.1ml

Ab-(001)-04046 Anti-TIF1 Alpha/TRIM24 转录中介因子Tif1α抗体 ,英文名: Anti-TIF1 ,规格: 0.2ml

Ab-(001)-04047 Anti-TIF1 beta/KAP1 转录中介因子Tif1β抗体 ,英文名: Anti-TIF1 ,规格: 0.2ml

Ab-(001)-04048 Anti-Phospho-TIF1beta (Ser824) 磷酸化转录中介因子Tif1β抗体 ,英文名: Anti-Phospho-TIF1beta ,规格: 0.1ml

Ab-(001)-04049 Anti-TIF1 gamma/Trim33 转录中介因子Tif1γ抗体 ,英文名: Anti-TIF1 ,规格: 0.2ml

Ab-(001)-04050 Anti-Tissue factor 组织因子抗体 ,英文名: Anti-Tissue ,规格: 0.1ml

Ab-(001)-04051 Anti-TFPI/LACI 组织因子途径抑制剂抗体 ,英文名: Anti-TFPI/LACI ,规格: 0.1ml

Ab-(001)-04052 Anti-TFPI-2 组织因子途径抑制剂-2抗体 ,英文名: Anti-TFPI-2 ,规格: 0.2ml

Ab-(001)-04053 Anti-TGF-alpha 转移生长因子–α抗体 ,英文名: Anti-TGF-alpha ,规格: 0.1ml

Ab-(001)-04054 Anti-TGF- Beta 1 转化生长因子β1抗体 ,英文名: Anti-TGF- ,规格: 0.1ml

Ab-(001)-04055 Anti-TGF-Beta 1 转化生长因子β1抗体 ,英文名: Anti-TGF-Beta ,规格: 0.1ml

Ab-(001)-04056 Anti-TIEG1 TGF-β诱导早期应答基因1抗体 ,英文名: Anti-TIEG1 ,规格: 0.2ml

Ab-(001)-04057 Anti-TGF-beta 2 转移生长因子β2抗体 ,英文名: Anti-TGF-beta ,规格: 0.1ml

Ab-(001)-04058 Anti-TGF beta 3 转移生长因子β3抗体 ,英文名: Anti-TGF ,规格: 0.1ml

Ab-(001)-04059 Anti-TGF Beta R1/TGFBR1 转移生长因子β受体1抗体 ,英文名: Anti-TGF ,规格: 0.1ml

Ab-(001)-04060 Anti-TGF beta R2/TGFBR2 转移生长因子β受体2抗体 ,英文名: Anti-TGF ,规格: 0.1ml

Ab-(001)-04061 Anti-TGF Beta R3 转移生长因子β受体3抗体 ,英文名: Anti-TGF ,规格: 0.2ml

Ab-(001)-04062 Anti-TGM3 转谷氨酰酶3抗体 ,英文名: Anti-TGM3 ,规格: 0.2ml

Ab-(001)-04063 Anti-Thioster-containing protein 1 按蚊硫酯包含蛋白-1抗体 ,英文名: Anti-Thioster-containing ,规格: 1ml

Ab-(001)-04064 Anti-ERdj5 ERdj5蛋白抗体 ,英文名: Anti-ERdj5 磷酸化活化复制因子2抗体规格: 0.2ml

Ab-(001)-04065 Anti-thrombin II 凝血酶Ⅱ抗体 ,英文名: Anti-thrombin ,规格: 0.2ml

Ab-(001)-04066 Anti-phospho-p38MAPK/MAPK14 (pThr180/pTyr182) 磷酸化p38MAPK抗体 ,英文名: Anti-phospho-p38MAPK/MAPK14 ,规格: 0.1ml


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企业名称

上海通蔚实业有限公司

企业信息已认证

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信用代码

310116003070684

成立日期

2014-04-16

注册资本

10

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磷酸化活化复制因子2抗体由上海通蔚实业有限公司为您提供,货号TE-KT-0079,规格:0.1ml/100μg 、0.2ml/200μg,CAS号:详见产品说明书,如您想了解更多关于磷酸化活化复制因子2抗体价格、磷酸化活化复制因子2抗体结构式、批发、用途等信息,欢迎咨询。除供应磷酸化活化复制因子2抗体外,还可为您提供百两金素A、甲氧醉椒素、酒石酸长春质碱等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海通蔚客户服务电话,售前、售后均可联系。

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