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当前位置: 上海通蔚 > 抗体/抗原 > 转录因子AP2α+β抗体

转录因子AP2α+β抗体

供货周期: 一周
品牌: EterLife
规格: 0.1ml/100μg 、0.2ml/200μg
货号: TE-KT-0032
CAS号: 详见产品说明书
报价: 面议
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产品介绍

转录因子AP2α+β抗体

〖别名〗Activating enhancer binding protein 2 alpha; Activating enhancer binding protein 2 beta; AP2TF; TFAP2; TFAP2A; TFAP2B; Transcription factor AP2 alpha; Transcription factor AP2 beta; AP2A_HUMAN; AP2B_HUMAN. 

〖浓度〗1mg/1ml 

〖规格〗0.2ml/200μg  

〖抗体来源〗Rabbit  

〖克隆类型〗polyclonal 

〖交叉反应〗Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep  

〖产品类型〗转录因子AP2α+β抗体一抗    

〖研究领域〗肿瘤 发育生物学 转录调节因子 结合蛋白 细胞分化 表观遗传学  

〖蛋白分子量〗predicted molecular weight: 48kDa 

〖性状〗Lyophilized or Liquid 

〖免疫原〗KLH conjugated synthetic peptide derived from human AP2 alpha + beta 

〖亚型〗IgG 

〖纯化方法〗affinity purified by Protein A 

〖储存液〗Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

〖产品应用〗WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

〖保存条件〗Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

〖产品介绍〗The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Function : Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. 

Subunit : Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with RALBP1 in a complex also containing EPN1 and NUMB during interphase and mitosis. Interacts with KCTD1; this interaction represses transcription activation. Interacts (via C-terminus) with CITED2 (via C-terminus); the interaction stimulates TFAP2A-transcriptional activation. Interacts (via N-terminus) with EP300 (via N-terminus); the interaction requires CITED2. 

Subcellular Location : Nuclear.

Post-translational modifications : Sumoylated on Lys-10; which inhibits transcriptional activity (Probable). 

DISEASE : Defects in TFAP2A are the cause of branchiooculofacial syndrome (BOFS) [MIM:113620]; also known as branchial clefts with characteristic facies, growth retardation, imperforate nasolacrimal duct, and premature aging or lip pseudocleft-hemangiomatous branchial cyst syndrome. BOFS is a rare autosomal dominant cleft palate craniofacial disorder with variable expressivity. The major features include cutaneous anomalies, ocular anomalies, characteristic facial appearance (malformed pinnae, oral clefts), and, less commonly, renal and ectodermal (dental and hair) anomalies.

Similarity : Belongs to the AP-2 family.

Database links : UniProtKB/Swiss-Prot: P05549.1 UniProtKB/Swiss-Prot: Q92481.2 

本公司产品现货供应,货期短,质量可靠。仅用于科研实验不应用于临床。我们用专业的态度,一流的服务,全程实验指导,让你的数据不在成为实验奇谈。选择优质的转录因子AP2α+β抗体,你的小伙伴都会惊呆的。本公司专业供应各种进口、国产一抗及二抗。代理品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种。让你的科研之路不再布满荆棘。

我们还可以为客户提供产品说明书。转录因子AP2α+β抗体拥有高纯度、高效价、高特异性的特点,可以应用于多种实验。免费送货上门,为您大大节省了时间和金钱。

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Ab-(001)-01637 Anti-CCR-3 细胞表面趋化因子受体3抗体 ,英文名: Anti-CCR-3 ,规格: 0.1ml

Ab-(001)-01638 Anti-CCR-4/CD194 细胞表面趋化因子受体4抗体 ,英文名: Anti-CCR-4/CD194 ,规格: 0.2ml

Ab-(001)-01639 Anti-CCR5 细胞表面趋化因子受体5抗体 ,英文名: Anti-CCR5 ,规格: 0.2ml

Ab-(001)-01640 Anti-CCR6/CD196 细胞表面趋化因子受体6抗体 ,英文名: Anti-CCR6/CD196 ,规格: 0.1ml

Ab-(001)-01641 Anti-CXCR6 细胞表面趋化因子受体6抗体 ,英文名: Anti-CXCR6 ,规格: 0.1ml

Ab-(001)-01642 Anti-CCR7/CD197 细胞表面趋化因子受体7抗体 ,英文名: Anti-CCR7/CD197 ,规格: 0.1ml

Ab-(001)-01643 anti-CXCL10/Gamma-IP-10 CXCL10趋化因子10/干扰素诱导蛋白10抗体 ,英文名: anti-CXCL10/Gamma-IP-10 ,规格: 0.2ml

Ab-(001)-01644 Anti-CXCR7/RDC1 细胞表面趋化因子受体7抗体 ,英文名: Anti-CXCR7/RDC1 ,规格: 0.2ml

Ab-(001)-01645 Anti-CCR-8 细胞表面趋化因子受体8抗体 ,英文名: Anti-CCR-8 ,规格: 0.2ml

Ab-(001)-01646 Anti-CCL25/CCR-9 细胞表面趋化因子受体9抗体 ,英文名: Anti-CCL25/CCR-9 ,规格: 0.2ml

Ab-(001)-01647 Anti-CCL28/MEC 粘膜相关上皮趋化因子28抗体 ,英文名: Anti-CCL28/MEC ,规格: 0.2ml

Ab-(001)-01648 Anti-CCR-10 细胞表面趋化因子受体10抗体 ,英文名: Anti-CCR-10 ,规格: 0.2ml

Ab-(001)-01649 Anti-CCRK 细胞周期相关激酶抗体 ,英文名: Anti-CCRK ,规格: 0.2ml

Ab-(001)-01650 Anti-CD10/CALLA CD10抗体 ,英文名: Anti-CD10/CALLA ,规格: 0.2ml

Ab-(001)-01651 Anti-CD105/Endoglin CD105抗体 ,英文名: Anti-CD105/Endoglin ,规格: 0.1ml

Ab-(001)-01652 Anti-CD117/c-kit/SCFR 干细胞生长因子受体/细胞表面分化抗原抗体 ,英文名: Anti-CD117/c-kit/SCFR ,规格: 0.1ml

Ab-(001)-01653 Anti-phospho-c-kit (Tyr936) 磷酸化原癌基因c-kit抗体 ,英文名: Anti-phospho-c-kit ,规格: 0.1ml

Ab-(001)-01654 Anti-Phospho-c-Kit (Tyr703) 磷酸化原癌基因c-kit抗体 ,英文名: Anti-Phospho-c-Kit ,规格: 0.1ml

Ab-(001)-01655 Anti-Phospho-c-Kit (Tyr719) 磷酸化原癌基因c-kit抗体 ,英文名: Anti-Phospho-c-Kit ,规格: 0.1ml

Ab-(001)-01656 Anti-CD133 antigen 造血干细胞抗原CD133抗体 ,英文名: Anti-CD133 ,规格: 0.1ml

Ab-(001)-01657 Anti-CD137/TNFRSF9 CD137抗体 ,英文名: Anti-CD137/TNFRSF9 ,规格: 0.2ml

Ab-(001)-01658 Anti-CD138/Syndecan-1 多配体蛋白聚糖1抗体 ,英文名: Anti-CD138/Syndecan-1 ,规格: 0.2ml

Ab-(001)-01659 Anti-CD146/MCAM 黑色素瘤细胞粘附分子CD146抗体 ,英文名: Anti-CD146/MCAM ,规格: 0.2ml

Ab-(001)-01660 Anti-CD141/THBD 凝血调节蛋白抗体 ,英文名: Anti-CD141/THBD ,规格: 0.1ml

Ab-(001)-01661 Anti-CD13/ANPEN CD13氨肽酶N抗体 ,英文名: Anti-CD13/ANPEN ,规格: 0.1ml

Ab-(001)-01662 Anti-CD14 内毒素受体抗体 ,英文名: Anti-CD14 ,规格: 0.1ml

Ab-(001)-01663 Anti-CD27/TNFRSF7 CD27抗体 ,英文名: Anti-CD27/TNFRSF7 ,规格: 0.2ml

Ab-(001)-01664 Anti-CD28 CD28抗体 ,英文名: Anti-CD28 ,规格: 0.1ml

Ab-(001)-01665 Anti-CD144/VECD 上皮型钙粘附分子抗体 ,英文名: Anti-CD144/VECD ,规格: 0.1ml

Ab-(001)-01666 Anti-CD147/TCSF 细胞外基质金属蛋白酶诱导因子抗体 ,英文名: Anti-CD147/TCSF ,规格: 0.1ml

Ab-(001)-01667 Anti-CD160/By55 NK细胞受体BY55抗体 ,英文名: Anti-CD160/By55 ,规格: 0.2ml

Ab-(001)-01668 Anti-CD161/NK1.1 CD161抗体 ,英文名: Anti-CD161/NK1.1 ,规格: 0.2ml

Ab-(001)-01669 Anti-CD163/M130 CD163抗体 ,英文名: Anti-CD163/M130 ,规格: 0.2ml

Ab-(001)-01670 Anti-CD166/ALCAM/MEMD 活化白细胞粘附分子抗体 ,英文名: Anti-CD166/ALCAM/MEMD ,规格: 0.2ml

Ab-(001)-01671 Anti-CD158a/KIR2DL1 NK细胞抑制性受体2DL1抗体 ,英文名: Anti-CD158a/KIR2DL1 ,规格: 0.2ml

Ab-(001)-01672 Anti-CD158e NK细胞抑制性受体3DL1抗体 ,英文名: Anti-CD158e ,规格: 0.2ml

Ab-(001)-01673 Anti-CD158b2 NK细胞抑制性受体2DL3抗体 ,英文名: Anti-CD158b2 ,规格: 0.2ml

Ab-(001)-01674 Anti-CD158 NK细胞抑制性受体2DL4抗体 ,英文名: Anti-CD158 ,规格: 0.2ml

Ab-(001)-01675 Anti-CD158i NK细胞抑制性受体2DS4抗体 ,英文名: Anti-CD158i ,规格: 0.2ml

Ab-(001)-01676 Anti-CD158e NK细胞抑制性受体3DL1抗体 ,英文名: Anti-CD158e ,规格: 0.2ml

Ab-(001)-01677 Anti-CD167a/DDR1 CD167a抗体 ,英文名: Anti-CD167a/DDR1 ,规格: 0.2ml

Ab-(001)-01678 Anti-CD169/sialoadhesin 唾液酸结合性免疫球蛋白样凝集素1抗体 ,英文名: Anti-CD169/sialoadhesin ,规格: 0.2ml

Ab-(001)-01679 Anti-CD170/Siglec-5 唾液酸结合性免疫球蛋白样凝集素5抗体 ,英文名: Anti-CD170/Siglec-5 ,规格: 0.2ml

Ab-(001)-01680 Anti-CD177/NB1 嗜中性粒细胞抗原CD177抗体 ,英文名: Anti-CD177/NB1 ,规格: 0.2ml

Ab-(001)-01681 Anti-CD17 CD17抗体 ,英文名: Anti-CD17 ,规格: 0.2ml

Ab-(001)-01682 Anti-CD226/DNAM-1 CD226抗体 ,英文名: Anti-CD226/DNAM-1 ,规格: 0.2ml

Ab-(001)-01683 Anti-CD229/SLAMF3 CD229抗体 ,英文名: Anti-CD229/SLAMF3 转录因子AP2α+β抗体规格: 0.2ml

Ab-(001)-01684 Anti-Integrin beta 2/CD18/LFA-1 整合素β2抗体 ,英文名: Anti-Integrin ,规格: 0.1ml

Ab-(001)-01685 Anti-Phospho-CD18 (Ser756/Thr758/759) 磷酸化整合素β2抗体 ,英文名: Anti-Phospho-CD18 ,规格: 0.1ml

 


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上海通蔚实业有限公司

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信用代码

310116003070684

成立日期

2014-04-16

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转录因子AP2α+β抗体由上海通蔚实业有限公司为您提供,货号TE-KT-0032,规格:0.1ml/100μg 、0.2ml/200μg,CAS号:详见产品说明书,如您想了解更多关于转录因子AP2α+β抗体价格、转录因子AP2α+β抗体结构式、批发、用途等信息,欢迎咨询。除供应转录因子AP2α+β抗体外,还可为您提供盐酸育亨宾、育亨宾、新甘草苷等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海通蔚客户服务电话,售前、售后均可联系。

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