Bone morphogenetic proteins (BMPs) constitute a subfamily within the
TGF-β superfamily of structurally related signaling proteins. Members of
this superfamily are widely distributed throughout the body, and are
involved in diverse physiological processes during both pre- and
postnatal life. Like BMP-7, BMP-4 is involved in the development and
maintenance of bone and cartilage. Reduced expression of BMP-4 is
associated with a number of bone diseases, including the heritable
disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived
BMP-4 is a fully active homodimeric protein consisting of two 106 amino
acid subunits, which correspond to amino acids 303-408 of the full
length BMP-4 precursor. The calculated molecular weight of Recombinant
Human BMP-4 (E.coli-derived) is 23.9 kDa.
Manufactured using all Animal-Free reagents.
Source: E.coli
Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4
AA Sequence (monomer): KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Calculated Molecular Weight: 23.9 kDa
Accession Number: P12644
Gene ID: 652
Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)
Note:
1mg will be provided as 2x500μg.
crossreactivity:
Human, Mouse, Rat, Salamander
Animal-Free Recombinant Human BMP-4 (E.coli derived)信息由上海远慕生物科技有限公司为您提供,如您想了解更多关于Animal-Free Recombinant Human BMP-4 (E.coli derived)报价、型号、参数等信息,欢迎来电或留言咨询。除供应Animal-Free Recombinant Human BMP-4 (E.coli derived)外,上海远慕生物科技有限公司还可为您提供大鼠 2 型次黄嘌呤核苷酸脱氢酶(IMPDH)(IMPDH2)ELISA试剂盒、大鼠Ⅰ型胶原交联羧基端肽(CTXⅠ)ELISA试剂盒、大鼠5羟色胺转运蛋白(SERT)ELISA试剂盒等产品,公司有专业的客户服务团队,是您值得信赖的合作伙伴。