原钙粘附蛋白α5抗体

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英文名称  Anti-PCDHA5

中文名称  原钙粘附蛋白α5抗体

别    名  Cadherin related neuronal receptor 6; CNR 6; CNR6; CNRN 6; CNRN6; CNRS 6; CNRS6; CRNR 6; CRNR6; Ortholog of mouse CNR6; PCDH alpha5; PCDHA 5; Protocadherin alpha 5; PCDA5_HUMAN.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Pig, Cow, Horse, Sheep

产品类型  一抗    

研究领域  神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白  

蛋白分子量  predicted molecular weight: 99kDa

性    状  Lyophilized or Liquid

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免 疫 原  KLH conjugated synthetic peptide derived from human PCDHA5

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA5 (Protocadherin alpha-5) is one of fifteen members of the protocadherin alpha protein family that is expressed in neurons. PCDHA5 is a 936 amino acid single-pass type I membrane protein containing 6 cadherin domains. Localized to the cell membrane, PCDHA5 functions as a calcium-dependent cell-adhesion protein that is present in synaptic junctions and is essential to the establishment and maintenance of certain cell-cell interactions. PCDHA5 is expressed as 3 isoforms produced by alternative splicing.

Function : Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location : Cell membrane; Single pass type I membrane protein.

原钙粘附蛋白α5抗体Similarity : Contains 6 cadherin domains.

Database links : UniProtKB/Swiss-Prot: Q9Y5H7.1