对氧磷酶3抗体

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英文名称  Anti-PON3

中文名称  对氧磷酶3抗体

别    名  paraoxonase 3; paraoxonase3; Pon3; PON3_HUMAN; Serum paraoxonase/lactonase 3; 2810004E20; AI786302; MGC95026.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog

产品类型  一抗    

研究领域  肿瘤 心血管 细胞生物 神经生物学 新陈代谢  

蛋白分子量  predicted molecular weight: 40kDa

性    状  Lyophilized or Liquid

对氧磷酶3抗体着国内抗体行业的崛起，我国自主品牌的抗体，都蛮多了，质量也不错，技术在逐渐成熟，价格也比国外的廉价的多，受到国内顾客的热捧，我们公司为了方便客户，特推出阴离子转运蛋白-1抗体规格15ug、30ug、50ug、100ug，15ug和30ug等，我们全国包邮，大中城市免费快递。抗体分子是生物学和医学领域用途最为广泛的蛋白分子。抗体作为疾病预防、诊断和治疗的制剂已有上百年的发展历史。随着生命科学研究的迅猛发展，抗体工程在生物技术领域越来越占有非常重要的地位。我公司可为您提供快速的、高质量的和经济的多克隆抗体制备服务，并将成为您在科研及生产中的得力助手。

免 疫 原  KLH conjugated synthetic peptide derived from human PON3

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

Function : Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.

Subunit : Homodimer.

Subcellular Location : Secreted, extracellular space

对氧磷酶3抗体Post-translational modifications : The signal sequence is not cleaved.

Similarity : Belongs to the paraoxonase family.

Database links : UniProtKB/Swiss-Prot: Q15166.3