浦肯野细胞萎缩相关蛋白1抗体

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英文名称  Anti-Puratrophin 1/PLEKHG4

中文名称  浦肯野细胞萎缩相关蛋白1抗体

别    名  ARHGEF44; PH domain-containing family G member 4; PKHG4_HUMAN; Pleckstrin homology domain containing family G (with RhoGef domain) member 4; member 4; Pleckstrin homology domain-containing family G member 4; PLEKHG 4; PLEKHG4; PRTPHN 1; PRTPHN1; Puratrophin 1; Puratrophin-1; Puratrophin1; Purkinje cell atrophy associated protein 1; Purkinje cell atrophy-associated protein 1; SCA 4; SCA4.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Cow, Horse, Sheep

产品类型  一抗    

研究领域  细胞生物 神经生物学  

蛋白分子量  predicted molecular weight: 131kDa

性    状  Lyophilized or Liquid

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免 疫 原  KLH conjugated synthetic peptide derived from human Puratrophin 1/PLEKHG4 (945-105aa)

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.

Function : Expressed in kidney, Leydig cells in the testis, epithelial cells in the prostate gland and Langerhans islet in the pancreas. Isoform 1 and isoform 3 are strongly expressed in Purkinje cells and to a lower extent in other neurons (at protein level). Widely expressed at low levels. More strongly expressed in testis and pancreas.

Tissue Specificity : Expressed in kidney, Leydig cells in thetestis, epithelial cells in the prostate gland and Langerhans isletin the pancreas. Isoform 1 and isoform 3 are strongly expressed inPurkinje cells and to a lower extent in other neurons (at proteinlevel). Widely expressed at low levels. More strongly expressed intestis and pancreas.

浦肯野细胞萎缩相关蛋白1抗体Similarity : Contains 1 DH (DBL-homology) domain.

Contains 1 PH domain.

Database links : UniProtKB/Swiss-Prot: Q58EX7.1