蛋白酶激活受体3抗体

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英文名称  Anti-PAR3

中文名称  蛋白酶激活受体3抗体

别    名  Proteinase Activated Receptor 3; coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thrombin receptor-like 2.

浓    度  1mg/1ml

规 格  0.1ml/100μg  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep

产品类型  一抗    

研究领域  心血管 细胞生物 信号转导 G蛋白偶联受体 G蛋白信号  

蛋白分子量  predicted molecular weight: 42kDa

性    状  Lyophilized or Liquid

蛋白酶激活受体3抗体的功能抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。

免 疫 原  KLH conjugated synthetic peptide derived from human PAR3

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-100  ICC=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Tissue specificity:

Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Function : Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Subcellular Location : Cell membrane.

蛋白酶激活受体3抗体Tissue Specificity : Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Post-translational modifications : A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity : Belongs to the G-protein coupled receptor 1 family.