NRNA尿苷酸合酶结构域蛋白2抗体

我公司专业供应RNA尿苷酸合酶结构域蛋白2抗体。了解更多关于的RNA尿苷酸合酶结构域蛋白2抗体英文名称RNA尿苷酸合酶结构域蛋白2抗体产品别名规格请看以下说明书。

英文名称  Anti-RPUSD2

中文名称  RNA尿苷酸合酶结构域蛋白2抗体

别    名  C15orf19; C18B11; C18B11 homolog; RNA pseudouridylate synthase domain containing 2; RNA pseudouridylate synthase domain containing protein 2; RNA pseudouridylate synthase domain-containing protein 2; RPUSD 2; RPUSD-2; RUSD2_HUMAN.

浓    度  1mg/1ml

规 格  0.2ml/200μg

RNA尿苷酸合酶结构域蛋白2抗体的功能：

抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。                                                                       

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Cow, Sheep

产品类型  一抗    

研究领域  

蛋白分子量  predicted molecular weight: 61kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human RPUSD2

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 RPUSD2, is a 545 amino acid member of the pseudouridine synthase rluA family and is encoded by a gene that is located on chromosome 15. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded RNA尿苷酸合酶结构域蛋白2抗体by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Similarity : Belongs to the pseudouridine synthase RluA family.

Database links : UniProtKB/Swiss-Prot: Q8IZ73.2