本公司是最专业RAS癌基因相关蛋白RAB6B抗体供应商,提供RAS癌基因相关蛋白RAB6B抗体的报价,泛素样蛋白Sumo2/3抗体咨询,
英文名称 Anti-RAB6B
中文名称 RAS癌基因相关蛋白RAB6B抗体
别 名 RAB6B; RAB6B member RAS oncogene family; RAB6B_HUMAN; Ras related protein Rab 6B; Ras-related protein Rab-6B; Small GTP binding protein; Small GTPase RAB6B.
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
RAS癌基因相关蛋白RAB6B抗体概述:
B淋巴细胞在抗原的刺激下,能够分化、增殖形成具有针对这种抗原分泌特异性抗体的能力。B细胞的这种能力和量是有限的,不可能持续分化增殖下去,因此产生免疫球蛋白的能力也是极其微小的。将这种B细胞与非分泌型的骨髓瘤细胞融合形成杂交瘤细胞,再进一步克隆化,这种克隆化的杂交瘤细胞是既具有瘤细胞的无限分裂的能力,又具有产生特异性抗体的B淋巴细胞的能力。将这种克隆化的杂交瘤细胞进行培养或注入小鼠腹水内即可获得大量的高效、单一的特异性抗体。这种技术即称为单克隆抗体技术。
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号
蛋白分子量 predicted molecular weight: 23kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RAB6B
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Function : Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Subunit : Interacts with CCDC64/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via C-terminus); the interaction is direct. Interacts (GDP-bound) with DYNLRB1.
Subcellular Location : Golgi apparatus membrane. Cytoplasmic vesicle. Colocalizes with BICD1 at vesicular structures that align along microtubules.
RAS癌基因相关蛋白RAB6B抗体Tissue Specificity : Predominantly expressed in brain.
Similarity : Belongs to the small GTPase superfamily. Rab family.
Database links : UniProtKB/Swiss-Prot: Q9NRW1.1