本公司是最专业类风湿因子抗体供应商,提供类风湿因子抗体的报价,泛素样蛋白Sumo2/3抗体咨询,
英文名称 Anti-RF/Rheumatoid Factor
中文名称 类风湿因子抗体
别 名 Ig kappa chain V-III region CLL; Rheumatoid factor; KV308_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
类风湿因子抗体概述:
B淋巴细胞在抗原的刺激下,能够分化、增殖形成具有针对这种抗原分泌特异性抗体的能力。B细胞的这种能力和量是有限的,不可能持续分化增殖下去,因此产生免疫球蛋白的能力也是极其微小的。将这种B细胞与非分泌型的骨髓瘤细胞融合形成杂交瘤细胞,再进一步克隆化,这种克隆化的杂交瘤细胞是既具有瘤细胞的无限分裂的能力,又具有产生特异性抗体的B淋巴细胞的能力。将这种克隆化的杂交瘤细胞进行培养或注入小鼠腹水内即可获得大量的高效、单一的特异性抗体。这种技术即称为单克隆抗体技术。
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human
产品类型 一抗
研究领域 细胞生物 免疫学 内分泌病
蛋白分子量 predicted molecular weight: 12kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Rheumatoid Factor (71-129aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Rheumatoid Factor is an antibody that recognizes the Fc portion of immuno-globulin G (IgG). Rheumatoid Factor and IgG form an immune complex that can activate various inflammatory processes in the body. A blood test is clinically used to detect the presence of Rheumatoid Factor, since high levels of Rheumatoid Factor are indicative of rheumatoid arthritis and Sjogren’s syndrome, an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. This factor is also associated with a higher tendency to develop non-joint manifestations of rheumatoid disease, such as rheumatoid nodules and rheumatoid lung disease.
类风湿因子抗体Subcellular Location : Secreted
Database links : UniProtKB/Swiss-Prot: P04207.2