视黄醛结合蛋白1抗体

本公司是最专业视黄醛结合蛋白1抗体供应商，提供视黄醛结合蛋白1抗体的报价，泛素样蛋白Sumo2/3抗体咨询，

英文名称  Anti-RLBP1L1

中文名称  视黄醛结合蛋白1抗体

别    名  Cellular retinaldehyde binding protein like; CRALBPL; FLJ37248; Retinaldehyde binding protein 1 like 1; RLBP1L1; CLVS1_HUMAN.

浓    度  1mg/1ml

规 格  0.2ml/200μg

视黄醛结合蛋白1抗体概述：

B淋巴细胞在抗原的刺激下，能够分化、增殖形成具有针对这种抗原分泌特异性抗体的能力。B细胞的这种能力和量是有限的，不可能持续分化增殖下去，因此产生免疫球蛋白的能力也是极其微小的。将这种B细胞与非分泌型的骨髓瘤细胞融合形成杂交瘤细胞，再进一步克隆化，这种克隆化的杂交瘤细胞是既具有瘤细胞的无限分裂的能力，又具有产生特异性抗体的B淋巴细胞的能力。将这种克隆化的杂交瘤细胞进行培养或注入小鼠腹水内即可获得大量的高效、单一的特异性抗体。这种技术即称为单克隆抗体技术。

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep  

产品类型  一抗    

研究领域  肿瘤 细胞生物 结合蛋白 肿瘤细胞生物标志物  

蛋白分子量  predicted molecular weight: 41kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human ICRF/REG1 alpha (211-260aa)

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 RLBP1L1 is a protein of unknown function. It has 45% identity with human CRALBP (Cellular retinaldehyde-binding protein) which carries 11-cis-retinol or 11-cis-retinaldehyde as endogenous ligands and may function as a substrate carrier protein that modulates interaction of these retinoids with visual cycle enzymes. RLBP1L1 is expressed in brain, and several human carcinoma cell lines.

Function : Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Subunit : Forms a complex with clathrin heavy chain and gamma-adaptin.

Subcellular Location : Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Early endosome membrane; Peripheral membrane protein.

视黄醛结合蛋白1抗体Tissue Specificity : Expressed mainly in the brain.

Similarity : Contains 1 CRAL-TRIO domain.

Database links : UniProtKB/Swiss-Prot: Q8IUQ0.1