Anti-CRP抗体，ihcCRP抗体一抗

Anti- CRP抗体，ihcCRP抗体一抗

From:ABCAM

Catalog Number :RS- 0155R

Quantity size : 0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent ) Background: Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated in innate immunity. CRP binds to ligands containing phosphocholine, SAP binds to amyloid fibrils, DNA, chromatin, fibronectin, C4-binding proteins and glycosaminoglycans. "Long" pentraxins have N-terminal extensions to the common pentraxin domain; one group, the neuronal pentraxins, may be involved in synapse formation and remodeling, and they may also be able to form heteromultimers.
Function : Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-CRP抗体，ihcCRP抗体一抗dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Subunit : Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
Subcellular Location : Secreted.Tissue Specificity : Found in plasma.Similarity : Belongs to the pentaxin family.Contains 1 pentaxin domain.Database links : UniProtKB/Swiss-Prot: P02741.1

Specificity : Anti- CRP is a rabbit polyclonal antibody

specific for CRP of Human, Mouse, Rat, Dog, Pig, Rabbit

use for western blotting,elisa,immunoprecipitation and immunohistochemistry

Protein G affinity chromatography purification, purity :>95%

Isotype: IgG

mol wt: 25kDa

Application : CRP抗体，ihcCRP抗体一抗

WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

KLH conjugated synthetic peptide derived from human CRP (151-200aa)

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user..

Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.