Anti-BMP-4抗体说明书

Rabbit Anti-BMP-4抗体说是门户 antibody
ABCAM

Cat. Number: Rs-1374R

Quantity size: 0.1ml (dilute with pH 7.4 0.01 M PBS or diluent of antibody)

Background:
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Specificity: · anti-BMP-4 is a rabbit Polyclonal antibody unconjugated

· specific for anti-BMP-4 of human ,rat and mouse

· use for western blotting, elisa, immunoprecipitation

and immunohistochemistry

· Protein A affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt:13/45 kDa

Application: · Western blotting: 1:100-500

· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Optimal working dilutions must be determined by the end user.

Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 oC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.