Anti-RGMC|反义导向分子RGMC抗体

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Anti-RGMC|反义导向分子RGMC抗体产品介绍：The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as Hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis.

【产品名称】：Anti-RGMC|反义导向分子RGMC抗体
【产品编号】：BYK-11475R
【规    格】：0.1ml/0.2ml
【相关标记】：Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP   APC   Biotin   Cy3   Cy5   Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   RBITC
【产品别名】：Mycoplasma Gallisepticum.
【浓    度】：1mg/1ml
【抗体来源】：Rabbit or Mouse or Goat
【克隆类型】：polyclonal or monoclonal
【产品类型】：一抗
【性    状】：Lyophilized or Liquid
【亚    型】：IgG
【纯化方法】：affinity purified by Protein A
【储 存 液】：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
【产品应用】：not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
【保存条件】：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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