产品名称:磷酸化KLF5抗体(Ser275)
中文名称:磷酸化KLF5抗体
英文名称:磷酸化KLF5抗体
产品编号:BYK-2020R
产品别名: Klf5; CKLF; Krueppel-like factor 5; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2; Basic transcription element-binding protein 2; BTE-binding protein 2; Krueppel-like factor 5; KLF5; basic transcription element-binding protein 2;BTEB2; intestine enriched krüppel-like factor; IKLF; Kruppel like factor 5; Transcription factor BTEB 2; Transcription factor BTEB2; KLF5_HUMAN.
本公司另供应其他标记:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC.
产品规格:100ug/200ug
产品浓度: 1mg/1ml
抗体来源:兔源、鼠源、其他
克 隆:单克隆抗体、多克隆抗体
抗体类型:一抗
性 状: 冻干粉或液体
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
![](https://img1.17img.cn/17img/old/NewsImags/images/201311483040.jpg)
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磷酸化KLF5抗体(Ser275)产品介绍:
Krüppel-like factors (KLFs) zinc finger-containing transcription factors with regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. KLF5, (also known as BTEB2 and IKLF), is essential for mouse embryo development. KLF5 activates many genes during cardiovascular remodeling, including PDGFa/b, Egr-1, PAI-1, iNOS, and VEGF receptors, making KLF a potential therapeutic target for cardiovascular disease. KLF5 also plays a role in angiogenesis and in development of several tumor types including breast, prostate, bladder, colon, esophagus, and skin. KLF5 is closely related to other of the KLF family members. However, KLF5 and KLF4 exhibit opposite effects on regulation of gene transcription, despite binding to similar, if not identical, cis-acting DNA sequences. In addition, KLF4 and 5 exert contrasting effects on cell proliferation in many instances; while KLF4 is an inhibitor of cell growth, KLF5 stimulates proliferation. KLF5 protein is enriched in intestinal tissue.