细胞分化蛋白SEPT11抗体

英文名称  Anti-Septin 11 

中文名称  细胞分化蛋白SEPT11抗体 

细胞分化蛋白SEPT11抗体别    名  SEP11_HUMAN; SEPT 11; Sept11; Septin-11; Septin11. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig

产品类型  一抗    

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、细胞分化蛋白SEPT11抗体品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  细胞生物 发育生物学 神经生物学 细胞凋亡 细胞分化 细胞骨架  

蛋白分子量  predicted molecular weight: 49kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human Septin 11 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

细胞分化蛋白SEPT11抗体产品介绍 Septins are members of a conserved family of cytoskeletal GTPases, specifically belonging to the large superclass of P loop GTPases. Septin proteins form homo- and hetero-oligomeric polymers that accumulate into higher-order filaments which may function as dynamic protein scaffolds. Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 11 is mainly present in brain tissue. It has been found to dominantly co-localize with microtubules and Actin stress fibers in HMEC cells and REF52 cells, and to partially co-localize with microtubules and stress fibers in HeLa cells. SEPT11 (the gene encoding Septin 11) is confined to the same tissues as those that express SEPT5, suggesting that SEPT11 and SEPT5 are components of a cell-specific septin complex.

Function : Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

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