尿素转运型糖蛋白A2抗体

英文名称  Anti-SLC14A2/UT-A 

中文名称  尿素转运型糖蛋白A2抗体 

尿素转运型糖蛋白A2抗体别    名  HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat

产品类型  一抗    

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、尿素转运型糖蛋白A2抗体品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  肿瘤 神经生物学 信号转导 通道蛋白 新陈代谢  

蛋白分子量  predicted molecular weight: 101kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human SLC14A2/UT-A 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

尿素转运型糖蛋白A2抗体产品介绍 Water balance is tightly regulated in the kidneys. Through urinary concentration mechanisms, the kidney prevents the unnecessary excrement of water, thereby protecting the body from dehydration. UT-A (Urea transporter, kidney), also known as SLC14A2 and HUT2, is a 920 amino acid multi-pass membrane protein that functions as a specialized low-affinity vasopressin-regulated urea-transporter. Expressed in the inner medulla of the kidney and localized to the apical membrane, UT-A mediates rapid transepithelial urea transport across the inner medullary collecting duct. There are two isoforms of UT-A that are produced as a result of alternative splicing events. Isoform 1 interacts with Snapin, a SNARE-associated protein, which is thought to help in its recruitment to the plasma membrane. Interestingly, isoform 1 expression is induced by low protein in the diet, whereas isoform 2 expression is induced by dehydration.

Function : Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

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