白细胞介素6受体β抗体IL-6Rβ

英文名称  Anti-IL-6R Beta/CD130/gp130

中文名称  白细胞介素6受体β抗体IL-6Rβ

白细胞介素6受体β抗体IL-6Rβ别    名  Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; CDw130; Oncostatin-M receptor subunit alpha; CD_antigen; CD130; GP130 RAPS; gp130 transducer chain; GP130-RAPS; IL6 ST; IL6R-beta; IL6ST.IL6R-beta.

浓    度  1mg/1ml

规 格  0.1ml/100μg  0.2ml/200μg    

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat

产品类型  一抗    

公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体，产品货期短、白细胞介素6受体β抗体IL-6Rβ品质保证、全国免邮，并提供抗体相应实验技术指导。

研究领域  细胞生物 免疫学 信号转导 细胞膜受体

蛋白分子量  predicted molecular weight: 99kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IL6R beta

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白细胞介素6受体β抗体IL-6Rβ产品介绍 CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Function : Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.

GUK1/Guanylate kinase  鸟苷酸激酶GMK抗体 规格 0.2ml

GUSB/beta glucuronidase  β葡萄糖醛酸苷酶抗体 规格 0.2ml

GYG1  糖原蛋白1抗体 规格 0.2ml

GYG2  糖原蛋白2抗体 规格 0.2ml

GYPB/CD235b  血型糖蛋白δ抗体 规格 0.2ml

GZMA/Granzyme A  颗粒酶A抗体 规格 0.2ml

GZMB/Granzyme B  颗粒酶B抗体 规格 0.1ml

H Cadherin/CDH13  心脏钙粘蛋白抗体 规格 0.2ml

H1N1 Hemagglutinin 1/HA probe  甲型流感病毒血凝素抗体 规格 0.2ml

H1N1 Hemagglutinin 1/Influenza A bp1  甲型流感病毒血凝素抗体 规格 0.2ml

H1N1 Hemagglutinin 2  甲型流感病毒血凝素抗体 规格 0.1ml

H1N1 白细胞介素6受体β抗体IL-6RβHemagglutinin 2  甲型流感病毒血凝素抗体 规格 0.1ml

H1N1 Matrix Protein 1  A型禽流感病毒H1N1蛋白抗体 规格 1ml

H1N1 matrix protein 2  甲型流感病毒M2抗体 规格 0.2ml

H1N1 Matrix Protein 2/Influenza A bp1   A型猪流感病毒H1N1-M2蛋白抗体 规格 0.2ml

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